The efficacy and safety of topical 10% potassium hydroxide for molluscum contagiosum: a systematic review and meta-analysis
DC Field | Value | Language |
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dc.contributor.author | Heo, Jae Young | - |
dc.contributor.author | Park, Tae Heum | - |
dc.contributor.author | Kim, Woo Il | - |
dc.date.accessioned | 2023-05-25T01:41:59Z | - |
dc.date.available | 2023-05-25T01:41:59Z | - |
dc.date.issued | 2022-04 | - |
dc.identifier.issn | 0954-6634 | - |
dc.identifier.issn | 1471-1753 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/22465 | - |
dc.description.abstract | Background Molluscum contagiosum (MC) is a self-limited cutaneous viral infection. Topical 10% potassium hydroxide (KOH) has been used for treating MC. However, it remains unclear whether it is beneficial or not to apply topical 10% KOH for treating MC. Methods To confirm the efficacy and safety of topical 10% KOH compared with placebo as well as other treatments for MC, meta-analysis was used. Up to September 2020, we performed a comprehensive search of literature based on three databases with following keywords including 'molluscum contagiosum' and 'potassium hydroxide'. Results Our meta-analyses demonstrated a significant difference between topical 10% KOH and placebo for complete clearance of MC (RR: 2.96, 95% CI: 1.69 - 5.17, p = .0001), while there were no statistical differences between them in the number of patients with adverse events (RR: 1.73, 95% CI: 0.67 - 4.45, p = .2562). Also, topical 10% KOH was as effective as mechanical treatments for MC (RR: 0.95, 95% CI: 0.84 - 1.07, p = .3833). Conclusion We demonstrate that application of topical 10% KOH may be one of effective and appropriate methods for the treatment of MC compared with awaiting spontaneous resolution due to its safety and effectiveness. | - |
dc.format.extent | 9 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Taylor & Francis | - |
dc.title | The efficacy and safety of topical 10% potassium hydroxide for molluscum contagiosum: a systematic review and meta-analysis | - |
dc.type | Article | - |
dc.publisher.location | 영국 | - |
dc.identifier.doi | 10.1080/09546634.2021.1898527 | - |
dc.identifier.scopusid | 2-s2.0-85110833002 | - |
dc.identifier.wosid | 000674065900001 | - |
dc.identifier.bibliographicCitation | Journal of Dermatological Treatment, v.33, no.3, pp 1682 - 1690 | - |
dc.citation.title | Journal of Dermatological Treatment | - |
dc.citation.volume | 33 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 1682 | - |
dc.citation.endPage | 1690 | - |
dc.type.docType | Review | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Dermatology | - |
dc.relation.journalWebOfScienceCategory | Dermatology | - |
dc.subject.keywordPlus | IMIQUIMOD 5-PERCENT CREAM | - |
dc.subject.keywordPlus | CHILDREN | - |
dc.subject.keywordPlus | CRYOTHERAPY | - |
dc.subject.keywordPlus | EXPERIENCE | - |
dc.subject.keywordPlus | TRIAL | - |
dc.subject.keywordAuthor | Molluscum contagiosum | - |
dc.subject.keywordAuthor | potassium hydroxide | - |
dc.subject.keywordAuthor | placebo | - |
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