The adverse effects of selenomethionine on skeletal muscle, liver, and brain in the steelhead trout (Oncorhynchus mykiss)
DC Field | Value | Language |
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dc.contributor.author | Lee, Jang-Won | - |
dc.contributor.author | Deng, Dong-Fang | - |
dc.contributor.author | Lee, Jinsu | - |
dc.contributor.author | Kim, Kiyoung | - |
dc.contributor.author | Jung, Hyun Jin | - |
dc.contributor.author | Choe, Youngshik | - |
dc.contributor.author | Park, Seung Hwa | - |
dc.contributor.author | Yoon, Minjung | - |
dc.date.accessioned | 2021-08-11T08:31:44Z | - |
dc.date.available | 2021-08-11T08:31:44Z | - |
dc.date.issued | 2020-11 | - |
dc.identifier.issn | 1382-6689 | - |
dc.identifier.issn | 1872-7077 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/2354 | - |
dc.description.abstract | Juvenile Oncorhynchus mykiss (average weight 22.3 g) were fed one of five selenomethionine diets (1.09, 8.79, 15.37, 30.79, or 61.58 mg Se/kg diet). After 4 weeks, hepatic catalase activity over 15.37 mg Se/kg diets was significantly decreased, and the glutathione peroxidase activity over 30.79 mg Se/kg diets was elevated compared to the controls. In the brain, the dopamine levels at 61.58 mg Se/kg diet and the serotonin levels over 15.37 mg Se/kg diets were significantly increased, whereas the 3,4-dihydroxyphenylacetic acid, homovanillic acid, and dopamine turnover, and the 5-hydroxyindoleacetic acid and serotonin turnover over 30.79 mg Se/kg diets were decreased. In muscle, the 3-nitrotyrosine level over 15.37 mg Se/kg diets, acetylcholine esterase activity over 30.79 mg Se/kg diets, and histological alterations over 8.79 mg Se/kg diets were increased. Our current results showed that selenomethionine disrupted dopamine and serotonin metabolism in the brain and damaged the neuromuscular system in skeletal muscle. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Elsevier BV | - |
dc.title | The adverse effects of selenomethionine on skeletal muscle, liver, and brain in the steelhead trout (Oncorhynchus mykiss) | - |
dc.type | Article | - |
dc.publisher.location | 네델란드 | - |
dc.identifier.doi | 10.1016/j.etap.2020.103451 | - |
dc.identifier.scopusid | 2-s2.0-85087206837 | - |
dc.identifier.wosid | 000583776900010 | - |
dc.identifier.bibliographicCitation | Environmental Toxicology and Pharmacology, v.80 | - |
dc.citation.title | Environmental Toxicology and Pharmacology | - |
dc.citation.volume | 80 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Environmental Sciences & Ecology | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalResearchArea | Toxicology | - |
dc.relation.journalWebOfScienceCategory | Environmental Sciences | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Toxicology | - |
dc.subject.keywordPlus | OXIDATIVE STRESS | - |
dc.subject.keywordPlus | DIETARY SELENOMETHIONINE | - |
dc.subject.keywordPlus | HETEROCYCLIC AMINES | - |
dc.subject.keywordPlus | CHRONIC EXPOSURE | - |
dc.subject.keywordPlus | SODIUM SELENITE | - |
dc.subject.keywordPlus | METABOLISM | - |
dc.subject.keywordPlus | GROWTH | - |
dc.subject.keywordPlus | ACETYLCHOLINESTERASE | - |
dc.subject.keywordPlus | NEUROTOXICITY | - |
dc.subject.keywordPlus | ANTIOXIDANT | - |
dc.subject.keywordAuthor | Selenium neurotoxicity | - |
dc.subject.keywordAuthor | Steelhead trout | - |
dc.subject.keywordAuthor | Neuromuscular system | - |
dc.subject.keywordAuthor | Histopathology | - |
dc.subject.keywordAuthor | Oxidative stress | - |
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