Current Status of Q Fever and the Challenge of Outbreak Preparedness in Korea: One Health Approach to Zoonosesopen access
- Authors
- Cho, Yun Sang; Park, Ji-Hyuk; Kim, Jong Wan; Lee, Jin-Ju; Youn, So Youn; Byeon, Hyeon Seop; Jeong, Hye Won; Kim, Dong-Min; Yu, Shi Nae; Yoon, Jang Won; Kwak, Dongmi; Yoo, Han Sang; Lee, Ji-Yeon; Kwon, Jeong-Ran; Hwang, Kyung-Won; Heo, Jung Yeon
- Issue Date
- Jun-2023
- Publisher
- 대한의학회
- Keywords
- QFever; Coxiella burnetii; Zoonoses; One Health
- Citation
- Journal of Korean Medical Science, v.38, no.24
- Journal Title
- Journal of Korean Medical Science
- Volume
- 38
- Number
- 24
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/24884
- DOI
- 10.3346/jkms.2023.38.e197
- ISSN
- 1011-8934
1598-6357
- Abstract
- Human Q fever, a zoonosis caused by Coxiella burnetii, presents with diverse clinical manifestations ranging from mild self-limited febrile illnesses to life-threatening complications such as endocarditis or vascular infection. Although acute Q fever is a benign illness with a low mortality rate, a large-scale outbreak of Q fever in the Netherlands led to concerns about the possibility of blood transfusion-related transmission or obstetric complications in pregnant women. Furthermore, a small minority (< 5%) of patients with asymptomatic or symptomatic infection progress to chronic Q fever. Chronic Q fever is fatal in 5-50% of patients if left untreated. In South Korea, Q fever in humans was designated as a notifiable infectious disease in 2006, and the number of Q fever cases has increased sharply since 2015. Nonetheless, it is still considered a neglected and under-recognized infectious disease. In this review, recent trends of human and animal Q fever in South Korea, and public health concerns regarding Q fever outbreaks are reviewed, and we consider how a One Health approach could be applied as a preventive measure to prepare for zoonotic Q fever outbreaks.
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Collections - College of Medicine > Department of Internal Medicine > 1. Journal Articles
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