Changes in Clinical Characteristics of Community-Acquired Acute Pyelonephritis and Antimicrobial Resistance of UropathogenicEscherichia coliin South Korea in the Past Decade
DC Field | Value | Language |
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dc.contributor.author | Kwon, Ki Tae | - |
dc.contributor.author | Kim, Bongyoung | - |
dc.contributor.author | Ryu, Seong-yeol | - |
dc.contributor.author | Wie, Seong-Heon | - |
dc.contributor.author | Kim, Jieun | - |
dc.contributor.author | Jo, Hyun-uk | - |
dc.contributor.author | Park, Se Yoon | - |
dc.contributor.author | Hong, Kyung-Wook | - |
dc.contributor.author | Kim, Hye In | - |
dc.contributor.author | Kim, Hyun Ah | - |
dc.contributor.author | Kim, Mi-Hee | - |
dc.contributor.author | Bae, Mi Hyun | - |
dc.contributor.author | Sohn, Yong-Hak | - |
dc.contributor.author | Lee, Yangsoon | - |
dc.contributor.author | Pai, Hyunjoo | - |
dc.date.accessioned | 2021-08-11T08:32:54Z | - |
dc.date.available | 2021-08-11T08:32:54Z | - |
dc.date.issued | 2020-09 | - |
dc.identifier.issn | 2079-6382 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/2501 | - |
dc.description.abstract | This study examined changes in the clinical characteristics of community-acquired acute pyelonephritis (CA-APN) in South Korea between the period 2010-2011 and 2017-2018. We recruited all CA-APN patients aged >= 19 years who visited eight hospitals in South Korea from September 2017 to August 2018, prospectively. Data collected were compared with those from the previous study in 2010-2012, with the same design and participation from 11 hospitals. A total of 617 patients were enrolled and compared to 818 patients' data collected in 2010-2011.Escherichia coliwas the most common causative pathogen of CA-APN in both periods (87.3% vs. 86.5%,p= 0.680).E. coliisolates showed significantly higher antimicrobial resistance against fluoroquinolone (32.0% vs. 21.6%,p< 0.001), cefotaxime (33.6% vs. 8.3%,p< 0.001), and trimethoprim/sulfamethoxazole (37.5% vs. 29.2%,p= 0.013) in 2017-2018 than in 2010-2011. Total duration of antibiotic treatment increased from 16.55 +/- 9.68 days in 2010-2011 to 19.12 +/- 9.90 days in 2017-2018 (p< 0.001); the duration of carbapenem usage increased from 0.59 +/- 2.87 days in 2010-2011 to 1.79 +/- 4.89 days in 2010-2011 (p< 0.001). The median hospitalization was higher for patients in 2017-2018 than in 2010-2011 (9 vs. 7 days,p< 0.001). In conclusion, antimicrobial resistance ofE. colito almost all antibiotic classes, especially third generation cephalosporin, increased significantly in CA-APN in South Korea. Consequently, total duration of antibiotic treatment, including carbapenem usage, increased. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Multidisciplinary Digital Publishing Institute (MDPI) | - |
dc.title | Changes in Clinical Characteristics of Community-Acquired Acute Pyelonephritis and Antimicrobial Resistance of UropathogenicEscherichia coliin South Korea in the Past Decade | - |
dc.type | Article | - |
dc.publisher.location | 스위스 | - |
dc.identifier.doi | 10.3390/antibiotics9090617 | - |
dc.identifier.scopusid | 2-s2.0-85091115837 | - |
dc.identifier.wosid | 000580729400001 | - |
dc.identifier.bibliographicCitation | Antibiotics, v.9, no.9 | - |
dc.citation.title | Antibiotics | - |
dc.citation.volume | 9 | - |
dc.citation.number | 9 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Infectious Diseases | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Infectious Diseases | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.subject.keywordPlus | URINARY-TRACT-INFECTIONS | - |
dc.subject.keywordPlus | ONSET ACUTE PYELONEPHRITIS | - |
dc.subject.keywordPlus | ESCHERICHIA-COLI | - |
dc.subject.keywordPlus | ANTIBIOTIC-TREATMENT | - |
dc.subject.keywordPlus | DISEASES-SOCIETY | - |
dc.subject.keywordPlus | RISK-FACTORS | - |
dc.subject.keywordPlus | SUSCEPTIBILITY | - |
dc.subject.keywordPlus | EPIDEMIOLOGY | - |
dc.subject.keywordPlus | BACTEREMIA | - |
dc.subject.keywordPlus | CARBAPENEM | - |
dc.subject.keywordAuthor | pyelonephritis | - |
dc.subject.keywordAuthor | urinary tract infection | - |
dc.subject.keywordAuthor | antimicrobial resistance | - |
dc.subject.keywordAuthor | Korea | - |
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