Radio-protective effects of Thymus quinquecostatus Celak extract in mice
DC Field | Value | Language |
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dc.contributor.author | Han, Eui Jeong | - |
dc.contributor.author | Im, Seung Tae | - |
dc.contributor.author | Ahn, Ginnae | - |
dc.contributor.author | Lee, Seung-Hong | - |
dc.date.accessioned | 2023-12-14T06:01:44Z | - |
dc.date.available | 2023-12-14T06:01:44Z | - |
dc.date.issued | 2023-09 | - |
dc.identifier.issn | 0969-8043 | - |
dc.identifier.issn | 1872-9800 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/25333 | - |
dc.description.abstract | Thymus quinquecostatus Celak (TQC) is an aromatic herb, that possesses a wide range of biological properties. In the present study, we investigated the radio-protective effect of TQC water extract (TQCW) in gamma ray -exposed splenocytes, a peripheral immune cell and mice. Our results showed that the treatment with TQCW dose-dependently increased the viability of splenocytes. TQCW significantly increased the proliferation of splenocytes by reducing the production of intracellular reactive oxygen species (ROS) in 2 Gy-exposed spleno-cytes. Moreover, TQCW enhanced the hemopoietic system as increasing the number of endogenous spleen colony-forming units, and the number and the proliferation of splenocytes in 7 Gy-exposed mice. These results suggest that TQCW protects mice by enhancing the splenocytes proliferation and hemopoietic systems following exposure to gamma rays. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Pergamon Press Ltd. | - |
dc.title | Radio-protective effects of Thymus quinquecostatus Celak extract in mice | - |
dc.type | Article | - |
dc.publisher.location | 영국 | - |
dc.identifier.doi | 10.1016/j.apradiso.2023.110881 | - |
dc.identifier.scopusid | 2-s2.0-85161055010 | - |
dc.identifier.wosid | 001013461400001 | - |
dc.identifier.bibliographicCitation | Applied Radiation and Isotopes, v.199 | - |
dc.citation.title | Applied Radiation and Isotopes | - |
dc.citation.volume | 199 | - |
dc.type.docType | Article; Early Access | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Nuclear Science & Technology | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Inorganic & Nuclear | - |
dc.relation.journalWebOfScienceCategory | Nuclear Science & Technology | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.subject.keywordPlus | RADIATION-INDUCED APOPTOSIS | - |
dc.subject.keywordPlus | IONIZING-RADIATION | - |
dc.subject.keywordPlus | ANTIOXIDANT | - |
dc.subject.keywordPlus | HEMATOPOIESIS | - |
dc.subject.keywordPlus | SPLENOCYTES | - |
dc.subject.keywordPlus | MODULATION | - |
dc.subject.keywordPlus | ECKOL | - |
dc.subject.keywordAuthor | Thymus quinquecostatus | - |
dc.subject.keywordAuthor | Water extract | - |
dc.subject.keywordAuthor | Gamma ray | - |
dc.subject.keywordAuthor | Radio -protective effect | - |
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