Association of Blood Pressure With Cardio-Renal Events and Mortality in Type 2 DM: A National Health Insurance Database
DC Field | Value | Language |
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dc.contributor.author | Kim, Bo-Yeon | - |
dc.contributor.author | Lee, Ji-In | - |
dc.contributor.author | Lee, Hye-Mi | - |
dc.contributor.author | Kim, So Hun | - |
dc.contributor.author | Mo, Eun Yeong | - |
dc.contributor.author | Son, Jang Won | - |
dc.contributor.author | Lee, Sihoon | - |
dc.contributor.author | Kim, Sungrae | - |
dc.date.accessioned | 2023-12-14T06:31:46Z | - |
dc.date.available | 2023-12-14T06:31:46Z | - |
dc.date.issued | 2023-07 | - |
dc.identifier.issn | 0021-972X | - |
dc.identifier.issn | 1945-7197 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/25569 | - |
dc.description.abstract | Context: The relationship of blood pressure (BP) with cardio-renal events and all-cause mortality in type 2 diabetes mellitus (T2DM) is still controversial. Objective: To investigate the optimal BP target in Korean individuals with T2DM. Methods: Using the Korean National Health Insurance System database, data of individuals with T2DM who underwent regular health checks from January 1, 2007, to December 31, 2007, were extracted (N = 1 800 073). Among them, a total of 326 593 individuals were included in the final study. The study population was divided into 7 groups according to their observed systolic blood pressure (SBP) (<110, 110-119, 120-129, 130-139, 140-149, 150-159, 160-169, and >= 170 mmHg) and diastolic blood pressure (DBP) (<65, 65-69, 70-74, 75-79, 80-84, 85-89, and >= 90 mmHg). Hazard ratios (HRs) of cardio-renal events and all-cause mortality according to BP categories were analyzed. Results: Compared with SBP of 120-129 mmHg and DBP of 75-79 mmHg, SBP of >= 130 mmHg and DBP of >= 80 mmHg were associated with an increase in HR of major cardiovascular adverse events (MACEs). SBP of 120-129 mmHg and DBP 75-79 mmHg were associated with the lowest HR of all-cause mortality. Both lower BP (SBP/DBP <120/70 mm) and higher BP (SBP/DBP >= 130/80 mmHg) were associated with an increased HR of all-cause mortality. Contrary to MACE, the lower the SBP, the lower the HR of renal events. Conclusion: In patients with T2DM, the optimal cutoff value of BP associated with a lower incidence of MACE and mortality may be 120-129 mmHg for SBP and 75-79 mmHg for DBP. However, lower SBP may be helpful for T2DM patients with a high risk of renal disease. | - |
dc.format.extent | 10 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | ENDOCRINE SOC | - |
dc.title | Association of Blood Pressure With Cardio-Renal Events and Mortality in Type 2 DM: A National Health Insurance Database | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1210/clinem/dgad404 | - |
dc.identifier.scopusid | 2-s2.0-85181178843 | - |
dc.identifier.wosid | 001072640300001 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, v.109, no.1, pp 227 - 236 | - |
dc.citation.title | JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM | - |
dc.citation.volume | 109 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 227 | - |
dc.citation.endPage | 236 | - |
dc.type.docType | Article; Early Access | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Endocrinology & Metabolism | - |
dc.relation.journalWebOfScienceCategory | Endocrinology & Metabolism | - |
dc.subject.keywordPlus | MICROVASCULAR COMPLICATIONS | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | GUIDELINE | - |
dc.subject.keywordAuthor | type 2 diabetes mellitus | - |
dc.subject.keywordAuthor | cardiovascular disease | - |
dc.subject.keywordAuthor | hypertension | - |
dc.subject.keywordAuthor | blood pressure | - |
dc.subject.keywordAuthor | Korea | - |
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