Clinical outcomes of interstitial lung abnormalities: a systematic review and meta-analysis
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Seok, Jinwoo | - |
dc.contributor.author | Park, Shinhee | - |
dc.contributor.author | Yoon, Eun Chong | - |
dc.contributor.author | Yoon, Hee-Young | - |
dc.date.accessioned | 2024-06-11T08:00:31Z | - |
dc.date.available | 2024-06-11T08:00:31Z | - |
dc.date.issued | 2024-03 | - |
dc.identifier.issn | 2045-2322 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/26083 | - |
dc.description.abstract | Interstitial lung abnormalities (ILA), incidental findings on computed tomography scans, have raised concerns due to their association with worse clinical outcomes. Our meta-analysis, which included studies up to April 2023 from PubMed/MEDLINE, Embase, and Cochrane Library, aimed to clarify the impact of ILA on mortality, lung cancer development, and complications from lung cancer treatments. Risk ratios (RR) with 95% confidence intervals (CI) were calculated for outcomes. Analyzing 10 studies on ILA prognosis and 9 on cancer treatment complications, we found that ILA significantly increases the risk of overall mortality (RR 2.62, 95% CI 1.94-3.54; I2 = 90%) and lung cancer development (RR 3.85, 95% CI 2.64-5.62; I2 = 22%). Additionally, cancer patients with ILA had higher risks of grade 2 radiation pneumonitis (RR 2.28, 95% CI 1.71-3.03; I2 = 0%) and immune checkpoint inhibitor-related interstitial lung disease (RR 3.05, 95% CI 1.37-6.77; I2 = 83%) compared with those without ILA. In conclusion, ILA significantly associates with increased mortality, lung cancer risk, and cancer treatment-related complications, highlighting the necessity for vigilant patient management and monitoring. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | NATURE PORTFOLIO | - |
dc.title | Clinical outcomes of interstitial lung abnormalities: a systematic review and meta-analysis | - |
dc.type | Article | - |
dc.publisher.location | 독일 | - |
dc.identifier.doi | 10.1038/s41598-024-57831-3 | - |
dc.identifier.scopusid | 2-s2.0-85188777649 | - |
dc.identifier.wosid | 001196356400005 | - |
dc.identifier.bibliographicCitation | SCIENTIFIC REPORTS, v.14, no.1 | - |
dc.citation.title | SCIENTIFIC REPORTS | - |
dc.citation.volume | 14 | - |
dc.citation.number | 1 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.subject.keywordPlus | LIGNITE DUST EXPLOSION | - |
dc.subject.keywordPlus | METAL HYDRIDE TIH2 | - |
dc.subject.keywordPlus | COAL-DUST | - |
dc.subject.keywordPlus | FLAME-PROPAGATION | - |
dc.subject.keywordPlus | SUPPRESSION | - |
dc.subject.keywordPlus | EXPLOSIBILITY | - |
dc.subject.keywordPlus | SIMULATION | - |
dc.subject.keywordPlus | BEHAVIORS | - |
dc.subject.keywordPlus | PRESSURE | - |
dc.subject.keywordAuthor | Immune checkpoint inhibitors | - |
dc.subject.keywordAuthor | Interstitial lung diseases | - |
dc.subject.keywordAuthor | Lung neoplasms | - |
dc.subject.keywordAuthor | Mortality | - |
dc.subject.keywordAuthor | Radiation pneumonitis | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(31538) 22, Soonchunhyang-ro, Asan-si, Chungcheongnam-do, Republic of Korea+82-41-530-1114
COPYRIGHT 2021 by SOONCHUNHYANG UNIVERSITY ALL RIGHTS RESERVED.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.