Cytosine-Rich Oligonucleotide and Electrochemically Reduced Graphene Oxide Nanocomposite for Ultrasensitive Electrochemical Ag<SUP>+</SUP> Sensing
DC Field | Value | Language |
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dc.contributor.author | Abbas, Nasir | - |
dc.contributor.author | Jang, Seung Joo | - |
dc.contributor.author | Kim, Tae Hyun | - |
dc.date.accessioned | 2024-06-11T08:01:13Z | - |
dc.date.available | 2024-06-11T08:01:13Z | - |
dc.date.issued | 2024-05 | - |
dc.identifier.issn | 2079-4991 | - |
dc.identifier.issn | 2079-4991 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/26198 | - |
dc.description.abstract | Silver ions (Ag+) are crucial in various fields, but pose environmental and health risks at high concentrations. This study presents a straightforward approach for the ultra-trace detection of Ag+, utilizing a composite of a cytosine-rich oligonucleotide (CRO) and an electrochemically reduced graphene oxide (ERGO). Initially, ERGO was synthesized on a glassy carbon electrode (GCE) through the reduction of graphene oxide (GO) via cyclic voltammetry. A methylene blue-tagged CRO (MB-CRO) was then anchored to the ERGO surface through pi-pi interactions, resulting in the formation of an MB-CRO-modified ERGO electrode (MB-CRO/ERGO-GCE). The interaction with Ag+ ions induced the formation of silver-mediated C-Ag+-C coordination, prompting the MB-CRO to adopt a hairpin structure. This conformational change led to the desorption of the MB-CRO from the ERGO-GCE, causing a variation in the redox current of the methylene blue associated with the MB-CRO. Electrochemical assays revealed that the sensor exhibits extraordinary sensitivity to Ag+ ions, with a linear detection range from 1 femtomolar (fM) to 100 nanomolars (nM) and a detection limit of 0.83 fM. Moreover, the sensor demonstrated high selectivity for Ag+ ions and several other benefits, including stability, reproducibility, and straightforward fabrication and operational procedures. Additionally, real sample analyses were performed using the modified electrode to detect Ag+ in tap and pond water samples, yielding satisfactory recovery rates. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | MDPI | - |
dc.title | Cytosine-Rich Oligonucleotide and Electrochemically Reduced Graphene Oxide Nanocomposite for Ultrasensitive Electrochemical Ag<SUP>+</SUP> Sensing | - |
dc.type | Article | - |
dc.publisher.location | 스위스 | - |
dc.identifier.doi | 10.3390/nano14090775 | - |
dc.identifier.scopusid | 2-s2.0-85193032331 | - |
dc.identifier.wosid | 001220571600001 | - |
dc.identifier.bibliographicCitation | NANOMATERIALS, v.14, no.9 | - |
dc.citation.title | NANOMATERIALS | - |
dc.citation.volume | 14 | - |
dc.citation.number | 9 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalResearchArea | Physics | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Physics, Applied | - |
dc.subject.keywordPlus | SILVER NANOPARTICLES | - |
dc.subject.keywordPlus | METAL-IONS | - |
dc.subject.keywordPlus | WATER | - |
dc.subject.keywordPlus | ASSAY | - |
dc.subject.keywordPlus | PAIRS | - |
dc.subject.keywordAuthor | reduced graphene oxide | - |
dc.subject.keywordAuthor | DNA hairpin | - |
dc.subject.keywordAuthor | silver ion | - |
dc.subject.keywordAuthor | electrochemical aptasensor | - |
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