Dynamic changes of systemic inflammation response index and systemic immune-inflammation index are associated with delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Yi, Ho Jun | - |
dc.contributor.author | Shin, Dong-Seong | - |
dc.contributor.author | Kim, Bum-Tae | - |
dc.date.accessioned | 2024-06-12T02:31:05Z | - |
dc.date.available | 2024-06-12T02:31:05Z | - |
dc.date.issued | 2024-05 | - |
dc.identifier.issn | 1052-3057 | - |
dc.identifier.issn | 1532-8511 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/26446 | - |
dc.description.abstract | Objectives: Delayed cerebral ischemia (DCI) is a factor contributing to poor outcome of aneurysmal subarachnoid hemorrhage (aSAH). Serial inflammatory response is known to affect the occurrence of DCI. The aim of this study was to evaluate associations of dynamic changes of various inflammatory markers with occurrence of DCI after aSAH. Methods: A total of 279 patients with interventional treatment for aSAH were enrolled, and dichotomized according to the occurrence of DCI. Various inflammatory markers, including systemic immune-inflammation index (SII), systemic inflammation response index (SIRI), and their dynamic changes were analyzed at four different time points. Receiver operating characteristic (ROC) curve analysis with area under the curve (AUC) and univariate, multivariate Cox regression analyses with hazard ratio (HR) and 95 % confidence interval (CI) were performed to identify predictors for DCI. Results: Differences of SII and SIRI values between DCI (+) and DCI (-) group were significantly higher at 5-7 days than at other time points (P < 0.001 and P < 0.001, respectively). SII and SIRI had higher predicting values for DCI occurrence than other inflammatory markers (AUC: 0.862, 95 % CI: 0.786-0.928; P < 0.001 and AUC: 0.851, 95 % CI: 0.769-0.913; P < 0.001, respectively). SII at 5-7 days (HR: 1.74, 95 % CI: 1.38-3.22, P = 0.020) and SIRI at 5-7 days (HR: 1.62, 95 % CI: 1.28-2.84, P = 0.035) were associated with occurrence of DCI. Conclusions: Dynamic changes of SII and SII might be predictors of DCI occurrence in patients with aSAH. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | ELSEVIER | - |
dc.title | Dynamic changes of systemic inflammation response index and systemic immune-inflammation index are associated with delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage | - |
dc.type | Article | - |
dc.publisher.location | 네델란드 | - |
dc.identifier.doi | 10.1016/j.jstrokecerebrovasdis.2024.107626 | - |
dc.identifier.scopusid | 2-s2.0-85188540426 | - |
dc.identifier.wosid | 001216253000001 | - |
dc.identifier.bibliographicCitation | JOURNAL OF STROKE & CEREBROVASCULAR DISEASES, v.33, no.5 | - |
dc.citation.title | JOURNAL OF STROKE & CEREBROVASCULAR DISEASES | - |
dc.citation.volume | 33 | - |
dc.citation.number | 5 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Neurosciences | - |
dc.relation.journalWebOfScienceCategory | Peripheral Vascular Disease | - |
dc.subject.keywordPlus | SERUM BIOMARKERS | - |
dc.subject.keywordPlus | PROGNOSTIC VALUE | - |
dc.subject.keywordPlus | SIRI | - |
dc.subject.keywordPlus | VASOSPASM | - |
dc.subject.keywordPlus | OUTCOMES | - |
dc.subject.keywordPlus | CANCER | - |
dc.subject.keywordPlus | RATIO | - |
dc.subject.keywordAuthor | Inflammation | - |
dc.subject.keywordAuthor | Lymphocytes | - |
dc.subject.keywordAuthor | Monocytes | - |
dc.subject.keywordAuthor | Neutrophils | - |
dc.subject.keywordAuthor | Subarachnoid hemorrhage | - |
dc.subject.keywordAuthor | Platelets | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(31538) 22, Soonchunhyang-ro, Asan-si, Chungcheongnam-do, Republic of Korea+82-41-530-1114
COPYRIGHT 2021 by SOONCHUNHYANG UNIVERSITY ALL RIGHTS RESERVED.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.