저칼슘식이동물모델에서 한국 자생 작은구슬산호말(Corallina pilulifera) 유래 해조칼슘이 뼈건강에 미치는 영향Analysis of the Effect of Calcium Supplementation Corallina pilulifera on Bone Health using Low-Calcium Dietary Animal Models
- Other Titles
- Analysis of the Effect of Calcium Supplementation Corallina pilulifera on Bone Health using Low-Calcium Dietary Animal Models
- Authors
- 이지안; 구선회; 황호원; 박용석; 곽인애; 이정석; 한영석; 김학재
- Issue Date
- Dec-2023
- Publisher
- 한국수산과학회
- Keywords
- Corallina pilulifera; Calcined powder; Low calcium dietary; Animal model; Korean source
- Citation
- 한국수산과학회지, v.56, no.6, pp 841 - 849
- Pages
- 9
- Journal Title
- 한국수산과학회지
- Volume
- 56
- Number
- 6
- Start Page
- 841
- End Page
- 849
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/26555
- ISSN
- 0374-8111
- Abstract
- Corallina pilulifera (CP) is prevalent along the Korean coastline and belongs to the Corallinaceae family, exhibiting growth throughout all seasons. This study confirmed the role of calcium supplementation through CP, calcined CP (CCP), and a commercial calcium powder, highlighting variations in dosage within animal models induced by a calcium-deficient diet. Analysis of calcium absorption was conducted by assessing the serum and urine calcium levels during the feeding periods. Serum calcium content was significantly higher in the control group (CON, 9.79 mg/dL) than in the calcium-deficient model (CDM, 6.15 mg/dL). The calcium content of urine was significantly higher than that of CON (0.20 mg/dL) compared with CDM (0.08 mg/dL). Reticular bone thickness showed no significant differences between the CON and CDM groups. Additionally, micro-CT results demonstrated a reduction in the trabecular volume and a significant difference between the number of strands and the average interval of the reticular bone. In conclusion, CP serves as a promising source of calcium supplementation. Therefore, these findings emphasize that CP is of sufficient value as an industrial material related to calcium metabolism.
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Collections - College of Medicine > Department of Clinical Pharmacology > 1. Journal Articles
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