Melanin Bleaching and Melanogenesis Inhibition Effects of Pediococcus acidilactici PMC48 Isolated from Korean Perilla Leaf Kimchi
DC Field | Value | Language |
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dc.contributor.author | Kim, Sukyung | - |
dc.contributor.author | Seo, Hoonhee | - |
dc.contributor.author | Al Mahmud, Hafij | - |
dc.contributor.author | Islam, Md Imtiazul | - |
dc.contributor.author | Sultana, Omme Fatema | - |
dc.contributor.author | Lee, Youngkyoung | - |
dc.contributor.author | Kim, Minhee | - |
dc.contributor.author | Song, Ho-Yeon | - |
dc.date.accessioned | 2021-08-11T08:34:18Z | - |
dc.date.available | 2021-08-11T08:34:18Z | - |
dc.date.issued | 2020-07 | - |
dc.identifier.issn | 1017-7825 | - |
dc.identifier.issn | 1738-8872 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/2665 | - |
dc.description.abstract | Overproduction and accumulation of melanin in the skin will darken the skin and cause skin disorders. So far, components that can inhibit tyrosinase, a melanin synthase of melanocytes, have been developed and used as ingredients of cosmetics or pharmaceutical products. However, most of existing substances can only inhibit the biosynthesis of melanin while melanin that is already synthesized and deposited is not directly decomposed. Thus, their effects in decreasing melanin concentration in the skin are weak. To overcome the limitation of existing therapeutic agents, we started to develop a substance that could directly biodegrade melanin. We screened traditional fermented food microorganisms for their abilities to direct biodegrade melanin. As a result, we found that a kimchi-derived Pediococcus acidilactici PMC48 had a direct melanin-degrading effect. This PMC48 strain is a new strain, different from P. acidilactici strains reported so far. It not only directly degrades melanin, but also has tyrosinase-inhibiting effect. It has a direct melanin-decomposition effect. It exceeds existing melanin synthesis-inhibiting technology. It is expected to be of high value as a raw material for melanin degradation drugs and cosmetics. | - |
dc.format.extent | 9 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | 한국미생물·생명공학회 | - |
dc.title | Melanin Bleaching and Melanogenesis Inhibition Effects of Pediococcus acidilactici PMC48 Isolated from Korean Perilla Leaf Kimchi | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.4014/jmb.2003.03007 | - |
dc.identifier.scopusid | 2-s2.0-85088848495 | - |
dc.identifier.wosid | 000557562700013 | - |
dc.identifier.bibliographicCitation | Journal of Microbiology and Biotechnology, v.30, no.7, pp 1051 - 1059 | - |
dc.citation.title | Journal of Microbiology and Biotechnology | - |
dc.citation.volume | 30 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 1051 | - |
dc.citation.endPage | 1059 | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002612071 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Biotechnology & Applied Microbiology | - |
dc.relation.journalResearchArea | Microbiology | - |
dc.relation.journalWebOfScienceCategory | Biotechnology & Applied Microbiology | - |
dc.relation.journalWebOfScienceCategory | Microbiology | - |
dc.subject.keywordPlus | GENOME SEQUENCE | - |
dc.subject.keywordPlus | IDENTIFICATION | - |
dc.subject.keywordPlus | ASSAY | - |
dc.subject.keywordAuthor | Pediococcus acidilactici PMC48 | - |
dc.subject.keywordAuthor | melanin | - |
dc.subject.keywordAuthor | tyrosinase | - |
dc.subject.keywordAuthor | perilla leaf kimchi | - |
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