Association between time to treatment and functional outcomes according to the Diffusion-Weighted Imaging Alberta Stroke Program Early Computed Tomography Score in endovascular stroke therapy
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, J-T | - |
dc.contributor.author | Cho, B-H | - |
dc.contributor.author | Choi, K-H | - |
dc.contributor.author | Park, M-S | - |
dc.contributor.author | Kim, B. J. | - |
dc.contributor.author | Park, J-M | - |
dc.contributor.author | Kang, K. | - |
dc.contributor.author | Lee, S. J. | - |
dc.contributor.author | Kim, J. G. | - |
dc.contributor.author | Cha, J-K | - |
dc.contributor.author | Kim, D-H | - |
dc.contributor.author | Nah, H-W | - |
dc.contributor.author | Park, T. H. | - |
dc.contributor.author | Park, S-S | - |
dc.contributor.author | Lee, K. B. | - |
dc.contributor.author | Lee, J. | - |
dc.contributor.author | Hong, K-S | - |
dc.contributor.author | Cho, Y-J | - |
dc.contributor.author | Park, H-K | - |
dc.contributor.author | Lee, B-C | - |
dc.contributor.author | Yu, K-H | - |
dc.contributor.author | Oh, M. S. | - |
dc.contributor.author | Kim, D-E | - |
dc.contributor.author | Ryu, W-S | - |
dc.contributor.author | Choi, J. C. | - |
dc.contributor.author | Kwon, J-H | - |
dc.contributor.author | Kim, W-J | - |
dc.contributor.author | Shin, D-, I | - |
dc.contributor.author | Sohn, S., I | - |
dc.contributor.author | Hong, J-H | - |
dc.contributor.author | Lee, J. S. | - |
dc.contributor.author | Bae, H-J | - |
dc.contributor.author | Saver, J. L. | - |
dc.contributor.author | Cho, K-H | - |
dc.date.accessioned | 2021-08-11T08:37:58Z | - |
dc.date.available | 2021-08-11T08:37:58Z | - |
dc.date.issued | 2020-02 | - |
dc.identifier.issn | 1351-5101 | - |
dc.identifier.issn | 1468-1331 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/3162 | - |
dc.description.abstract | Background and purpose The rate at which the chance of a good outcome of endovascular stroke therapy (EVT) decays with time when eligible patients are selected by baseline diffusion-weighted magnetic resonance imaging (DWI-MRI) and whether ischaemic core size affects this rate remain to be investigated. Methods This study analyses a prospective multicentre registry of stroke patients treated with EVT based on pretreatment DWI-MRI that was categorized into three groups: small [Diffusion-Weighted Imaging Alberta Stroke Program Early Computed Tomography Score (DWI-ASPECTS)] (8-10), moderate (5-7) and large (<5) cores. The main outcome was a good outcome at 90 days (modified Rankin Scale 0-2). The interaction between onset-to-groin puncture time (OTP) and DWI-ASPECTS categories regarding functional outcomes was investigated. Results Ultimately, 985 patients (age 69 +/- 11 years; male 55%) were analysed. Potential interaction effects between the DWI-ASPECTS categories and OTP on a good outcome at 90 days were observed (P-interaction = 0.06). Every 60-min delay in OTP was associated with a 16% reduced likelihood of a good outcome at 90 days amongst patients with large cores, although no associations were observed amongst patients with small to moderate cores. Interestingly, the adjusted rates of a good outcome at 90 days steeply declined between 65 and 213 min of OTP and then remained smooth throughout 24 h of OTP (P-nonlinearity = 0.15). Conclusions Our study showed that the probability of a good outcome after EVT nonlinearly decreased, with a steeper decline at earlier OTP than at later OTP. Discrepant effects of OTP on functional outcomes by baseline DWI-ASPECTS categories were observed. Thus, different strategies for EVT based on time and ischaemic core size are warranted. | - |
dc.format.extent | 9 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Blackwell Publishing Inc. | - |
dc.title | Association between time to treatment and functional outcomes according to the Diffusion-Weighted Imaging Alberta Stroke Program Early Computed Tomography Score in endovascular stroke therapy | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1111/ene.14083 | - |
dc.identifier.scopusid | 2-s2.0-85076557249 | - |
dc.identifier.wosid | 000491522200001 | - |
dc.identifier.bibliographicCitation | European Journal of Neurology, v.27, no.2, pp 343 - 351 | - |
dc.citation.title | European Journal of Neurology | - |
dc.citation.volume | 27 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 343 | - |
dc.citation.endPage | 351 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalWebOfScienceCategory | Clinical Neurology | - |
dc.relation.journalWebOfScienceCategory | Neurosciences | - |
dc.subject.keywordPlus | ACUTE ISCHEMIC-STROKE | - |
dc.subject.keywordPlus | THROMBECTOMY | - |
dc.subject.keywordPlus | REPERFUSION | - |
dc.subject.keywordPlus | TRIAL | - |
dc.subject.keywordAuthor | acute ischaemic stroke | - |
dc.subject.keywordAuthor | DWI-ASPECTS | - |
dc.subject.keywordAuthor | endovascular therapy | - |
dc.subject.keywordAuthor | time to treatment | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(31538) 22, Soonchunhyang-ro, Asan-si, Chungcheongnam-do, Republic of Korea+82-41-530-1114
COPYRIGHT 2021 by SOONCHUNHYANG UNIVERSITY ALL RIGHTS RESERVED.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.