'Sirim' (Cold) Pain as a Common Symptom in Korean Patients with Clinically Suspected Small-Fiber Neuropathy
DC Field | Value | Language |
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dc.contributor.author | Cho, Eun Bin | - |
dc.contributor.author | Seok, Jin Myoung | - |
dc.contributor.author | Min, Ju-Hong | - |
dc.contributor.author | Suh, Bum Chun | - |
dc.contributor.author | Park, Ki-Jong | - |
dc.contributor.author | Kim, Byoung Joon | - |
dc.date.accessioned | 2021-08-11T09:24:04Z | - |
dc.date.available | 2021-08-11T09:24:04Z | - |
dc.date.issued | 2019-10 | - |
dc.identifier.issn | 1738-6586 | - |
dc.identifier.issn | 2005-5013 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/4175 | - |
dc.description.abstract | Background and Purpose Diagnosing small-fiber neuropathy (SFN) is challenging because there is no gold-standard test and few diagnostic tests. This study investigated the clinical symptom profile and its associations with the results of quantitative sensory testing (QST) and the quantitative sudomotor axon reflex test (QSART) as well as the quality of life (QOL) in patients with clinically suspected SFN. Methods This study involved 63 patients with clinically suspected length-dependent SFN. Assessments were performed using QST, QSART, SFN Symptoms Inventory Questionnaire, Neuropathic Pain Symptom Inventory, 'Sirim' frequency and Sirim' (cold) pain severity, and 36-item Short-Form Health Survey. Multiple logistic and linear regression analyses were performed to predict risk factors for QST or QSART abnormalities and QOL, respectively. Results 'Sirim' and 'Sirim' pain was the most-common (84%) and the most-severe complaint (mean score of 6.3 on a numerical rating scale ranging from 0 to 10) in patients with clinically suspected SFN. The findings of QST [cold detection threshold (CDT)] and QSART were abnormal in 71% (n=45/57) and 62% (n=39/56) of the patients, respectively. An abnormal CDT was correlated with more-severe stabbing pain (odds ratio=2.23, 95% CI=1.02-4.87, p=0.045). Restless-leg symptoms (beta=-7.077) and pressure-evoked pain (beta=-5.034) were independent predictors of the physical aspects of QOL. Conclusions Skim pain, similar to cold pain, should be considered a major neuropathic pain in SFN. Among pain characteristics, stabbing pain of a spontaneous paroxysmal nature may be more pronounced in the setting of dysfunctional A delta fibers with functional autonomic C fibers. | - |
dc.format.extent | 8 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | 대한신경과학회 | - |
dc.title | 'Sirim' (Cold) Pain as a Common Symptom in Korean Patients with Clinically Suspected Small-Fiber Neuropathy | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.3988/jcn.2019.15.4.480 | - |
dc.identifier.scopusid | 2-s2.0-85075415240 | - |
dc.identifier.wosid | 000491217300008 | - |
dc.identifier.bibliographicCitation | Journal of Clinical Neurology, v.15, no.4, pp 480 - 487 | - |
dc.citation.title | Journal of Clinical Neurology | - |
dc.citation.volume | 15 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 480 | - |
dc.citation.endPage | 487 | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002510426 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalWebOfScienceCategory | Clinical Neurology | - |
dc.subject.keywordPlus | DIAGNOSTIC-CRITERIA | - |
dc.subject.keywordPlus | ETHNIC-DIFFERENCES | - |
dc.subject.keywordPlus | HYPERALGESIA | - |
dc.subject.keywordPlus | TOLERANCE | - |
dc.subject.keywordPlus | SKIN | - |
dc.subject.keywordAuthor | small fiber neuropathy | - |
dc.subject.keywordAuthor | sensory | - |
dc.subject.keywordAuthor | autonomic | - |
dc.subject.keywordAuthor | cold | - |
dc.subject.keywordAuthor | pain | - |
dc.subject.keywordAuthor | quality of life | - |
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