Histologic Analysis with the Newly Designed Exoskeleton Seal((R)) Stent-Graft in the Porcine Abdominal Aorta
DC Field | Value | Language |
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dc.contributor.author | Park, Jung-Hoon | - |
dc.contributor.author | Cho, Young Kwon | - |
dc.contributor.author | Her, Keun | - |
dc.contributor.author | Jeon, Yong Sun | - |
dc.contributor.author | Kim, Jeong Ho | - |
dc.contributor.author | Seo, Tae-Seok | - |
dc.contributor.author | Song, Myung Gyu | - |
dc.date.accessioned | 2021-08-11T09:24:32Z | - |
dc.date.available | 2021-08-11T09:24:32Z | - |
dc.date.issued | 2019-09 | - |
dc.identifier.issn | 0174-1551 | - |
dc.identifier.issn | 1432-086X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/4272 | - |
dc.description.abstract | PurposeTo investigate the technical feasibility of a novel exoskeleton Seal((R)) stent-graft and analyze early histologic changes in the porcine abdominal aorta.Materials and MethodsSix pigs received an abdominal stent-graft (Group I), and six received an iliac branch stent-graft (Group II). Groups were subdivided as follows: Group Ia, which received three bifurcated main-body stent-grafts; Group Ib, which received three bifurcated main-body stent-grafts with both iliac graft-stents; Group IIa, which received three simple uni-iliac tapered stent-grafts; and Group IIb, which received three uni-iliac tapered tapered stent-grafts with right straight limb and left branched limb. Statistical analyses were performed with the Wilcoxon signed-rank test and mixed-model regression analysis.ResultsThe primary technical success rate (<24h) was 83% because of two acute thromboses in the lumen of the stented abdominal aorta immediately after stent-graft placement. At 4weeks, late thrombosis occurred in two pigs. Higher mean neointimal hyperplasia areas (23.5% vs. 16.2%; P=.047), neointimal hyperplasia thicknesses (545.5 mu m vs. 422.2 mu m; P=.001), and degrees of collagen deposition (2.71 vs. 2.33; P=.002) were observed at the bare-metal stent-graft compared with the proximal exoskeleton portion of the stent-graft, with no significant differences between the patent and occluded groups or among the four types of stent-grafts.ConclusionsThe exoskeleton stent-graft demonstrates 66% of patency rate during 1-month follow-up due to four cases of thromboses; however, the endothelialization on the junction of proximal graft showed no significant differences between the patent and occluded groups. Further studies should investigate long-term outcomes with prolonged neointimal hyperplasia. | - |
dc.format.extent | 12 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Springer Verlag | - |
dc.title | Histologic Analysis with the Newly Designed Exoskeleton Seal((R)) Stent-Graft in the Porcine Abdominal Aorta | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1007/s00270-019-02261-2 | - |
dc.identifier.scopusid | 2-s2.0-85067690895 | - |
dc.identifier.wosid | 000484018100016 | - |
dc.identifier.bibliographicCitation | CardioVascular and Interventional Radiology, v.42, no.9, pp 1331 - 1342 | - |
dc.citation.title | CardioVascular and Interventional Radiology | - |
dc.citation.volume | 42 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 1331 | - |
dc.citation.endPage | 1342 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Cardiac & Cardiovascular Systems | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.subject.keywordPlus | ENDOVASCULAR REPAIR | - |
dc.subject.keywordPlus | ANEURYSM | - |
dc.subject.keywordAuthor | Exoskeleton stent-graft | - |
dc.subject.keywordAuthor | Animal studies | - |
dc.subject.keywordAuthor | Porcine abdominal aorta | - |
dc.subject.keywordAuthor | Thrombotic occlusions | - |
dc.subject.keywordAuthor | Neointimal hyperplasia | - |
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