Clinical characteristics and risk factors for gout flare during the postsurgical period
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Jeong, Hyemin | - |
dc.contributor.author | Jeon, Chan Hong | - |
dc.date.accessioned | 2021-08-11T09:43:31Z | - |
dc.date.available | 2021-08-11T09:43:31Z | - |
dc.date.issued | 2019-07-25 | - |
dc.identifier.issn | 2523-3106 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/4375 | - |
dc.description.abstract | Objectives: To evaluate the clinical features and risk factors for gout flare during postsurgical period in patients who were previously diagnosed with gout. Methods: Seventy patients who had histories of gout and had been consulted in the rheumatologic clinic before surgery under general anesthesia were included. Clinical characteristics of patients who developed a postsurgical gout flare were compared with those of patients who did not develop gout flare. Results: Among 70 patients, 31 (44.3%) developed gout flare during the postsurgical period. Mean intervals from surgery to gout flare was 3.7days. Flares tended to involve monoarticular joints (61.3%) and affect lower extremity joints (83.9%). Knee joints (26%) and foot joints except the first metatarsophalangeal (MTP) joint (26%) were more frequently involved than the first MTP joint (13%). Presurgical uric acid level >= 9mg/dL (OR 3.77, 95% CI 1.28-11.10, p = 0.016) and amount of uric acid changes between before and after surgery (OR 1.62, 95% CI 1.21-2.18, p = 0.001) were risk factors for postsurgical gout flare. Taking allopurinol reduced the risk of postsurgical gout flare (OR 0.15, 95% CI 0.05-0.45, p = 0.001). Operation time, amount of blood loss during surgery, and surgery site were not significantly associated with postsurgical gout flare. Conclusions: Adequate uric acid control before surgery could prevent the postsurgical gout flare. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.title | Clinical characteristics and risk factors for gout flare during the postsurgical period | - |
dc.type | Article | - |
dc.publisher.location | 영국 | - |
dc.identifier.doi | 10.1186/s42358-019-0075-7 | - |
dc.identifier.scopusid | 2-s2.0-85070646380 | - |
dc.identifier.wosid | 000477566100002 | - |
dc.identifier.bibliographicCitation | Advances in rheumatology, v.59 | - |
dc.citation.title | Advances in rheumatology | - |
dc.citation.volume | 59 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Rheumatology | - |
dc.relation.journalWebOfScienceCategory | Rheumatology | - |
dc.subject.keywordPlus | HYPERURICEMIA | - |
dc.subject.keywordPlus | POPULATION | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | MONOCYTES | - |
dc.subject.keywordPlus | URATE | - |
dc.subject.keywordAuthor | Gout | - |
dc.subject.keywordAuthor | Surgery | - |
dc.subject.keywordAuthor | Uric acid | - |
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