Improved detection of metastatic lymph nodes in oesophageal squamous cell carcinoma by combined interpretation of fluorine-18-fluorodeoxyglucose positron-emission tomography/computed tomography
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Ji Young | - |
dc.contributor.author | Kim, Young Hwan | - |
dc.contributor.author | Park, Yong-Jin | - |
dc.contributor.author | Park, Soo Bin | - |
dc.contributor.author | Chung, Hyun Woo | - |
dc.contributor.author | Zo, Jae Il | - |
dc.contributor.author | Shim, Young Mog | - |
dc.contributor.author | Lee, Kyung Soo | - |
dc.contributor.author | Choi, Joon Young | - |
dc.date.accessioned | 2021-08-11T09:43:48Z | - |
dc.date.available | 2021-08-11T09:43:48Z | - |
dc.date.issued | 2019-06-22 | - |
dc.identifier.issn | 1740-5025 | - |
dc.identifier.issn | 1470-7330 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/4461 | - |
dc.description.abstract | BackgroundWe sought to evaluate the diagnostic performance of fluorine-18-fluorodeoxyglucose positron-emission tomography/computed tomography (F-18-FDG PET/CT) in the detection of metastatic lymph nodes by combined interpretation of PET/CT images in patients with oesophageal squamous cell carcinoma.MethodsTwo hundred three patients with oesophageal squamous cell carcinoma underwent F-18-FDG PET/CT before oesophagectomy and lymph node dissection. Maximum standardized uptake value (SUVmax), mean Hounsfield unit (HU), short axis diameter (size), and visual CT attenuation (high, iso-, low) were evaluated on noncontrast CT and PET images following PET/CT scan. In this combined interpretation protocol, the high attenuated lymph nodes were considered benign, even if the SUVmax value was high. The diagnostic accuracy of each method was compared using the postoperative histologic result as a reference standard.ResultsA total of 1099 nodal stations were dissected and 949 nodal stations were proven to demonstrate metastasis. SUVmax and size of the malignant lymph nodes were higher than those of the benign nodes, and visual CT attenuation was significantly different among the two groups (P<0.001). Using cutoff values of 2.6 for SUVmax and 10.2mm for size, the combined interpretation of an SUVmax of more than 2.6 with iso- or low CT attenuation [area under the curve (AUC): 0.846, 95% confidence interval (CI): 0.824-0.867] showed significantly better diagnostic performance for detecting malignant lymph nodes than SUVmax only (AUC: 0.791, 95% CI: 0.766-0.815) and size (AUC: 0.693, 95% CI: 0.665-0.720) methods (P<0.001) in a receiver operating characteristic curve analysis.ConclusionsThe diagnostic accuracy of PET/CT for nodal metastasis in oesophageal squamous cell carcinoma was improved by the combined interpretation of F-18-FDG uptake and visual CT attenuation pattern. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | e-med | - |
dc.title | Improved detection of metastatic lymph nodes in oesophageal squamous cell carcinoma by combined interpretation of fluorine-18-fluorodeoxyglucose positron-emission tomography/computed tomography | - |
dc.type | Article | - |
dc.publisher.location | 영국 | - |
dc.identifier.doi | 10.1186/s40644-019-0225-5 | - |
dc.identifier.scopusid | 2-s2.0-85068435644 | - |
dc.identifier.wosid | 000472511600001 | - |
dc.identifier.bibliographicCitation | Cancer Imaging, v.19 | - |
dc.citation.title | Cancer Imaging | - |
dc.citation.volume | 19 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Oncology | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Oncology | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.subject.keywordPlus | INTEGRATED FDG PET/CT | - |
dc.subject.keywordPlus | LUNG-CANCER | - |
dc.subject.keywordPlus | COMPUTED-TOMOGRAPHY | - |
dc.subject.keywordPlus | F-18-FDG PET/CT | - |
dc.subject.keywordPlus | CT | - |
dc.subject.keywordPlus | PARAMETERS | - |
dc.subject.keywordPlus | SURVIVAL | - |
dc.subject.keywordPlus | SPREAD | - |
dc.subject.keywordPlus | INVOLVEMENT | - |
dc.subject.keywordPlus | PREDICTION | - |
dc.subject.keywordAuthor | F-18-FDG | - |
dc.subject.keywordAuthor | PET | - |
dc.subject.keywordAuthor | CT | - |
dc.subject.keywordAuthor | Oesophageal cancer | - |
dc.subject.keywordAuthor | Lymph node metastasis | - |
dc.subject.keywordAuthor | SUVmax | - |
dc.subject.keywordAuthor | CT attenuation | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(31538) 22, Soonchunhyang-ro, Asan-si, Chungcheongnam-do, Republic of Korea+82-41-530-1114
COPYRIGHT 2021 by SOONCHUNHYANG UNIVERSITY ALL RIGHTS RESERVED.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.