Efficacy of a novel hemostatic adhesive powder in patients with refractory upper gastrointestinal bleeding: a pilot study
- Authors
- Park, Jin-Seok; Bang, Byung Wook; Hong, Su Jin; Lee, Eunhye; Kwon, Kye Sook; Kim, Hyung Kil; Shin, Yong Woon; Lee, Don Haeng
- Issue Date
- May-2019
- Publisher
- Georg Thieme Verlag
- Keywords
- 소화기내과학
- Citation
- Endoscopy, v.51, no.5, pp 458 - 462
- Pages
- 5
- Journal Title
- Endoscopy
- Volume
- 51
- Number
- 5
- Start Page
- 458
- End Page
- 462
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/4566
- DOI
- 10.1055/a-0809-5276
- ISSN
- 0013-726X
1438-8812
- Abstract
- Background A new hemostatic adhesive powder (UI-EWD) has been developed to reduce the high re-bleeding rates associated with the currently available hemostatic powders. The current study aimed to assess the efficacy of UI-EWD as a salvage therapy for the treatment of refractory upper gastrointestinal bleeding (UGIB). Methods A total of 17 consecutive patients who had failed to achieve hemostasis with conventional endoscopic procedures and had undergone treatment with UI-EWD for endoscopic hemostasis in refractory UGIB were prospectively enrolled in the study. We evaluated the success rate of initial hemostasis and rate of re-bleeding within 30 days. Results All patients underwent successful UI-EWD application at the bleeding site. Initial hemostasis occurred in 16/17 patients (94%). Re-bleeding within 30 days occurred in 3/16 patients (19%) who had achieved initial hemostasis. In the second-look endoscopy after 24 hours, hydrogel from UI-EWD was found attached at the bleeding site in 11/16 patients (69%). Conclusion UI-EWD has a high success rate for initial hemostasis in refractory UGIB and shows promising results in the prevention of re-bleeding.
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Collections - College of Medicine > Department of Internal Medicine > 1. Journal Articles
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