Case Series of Morbihan Disease (Extreme Eyelid Oedema Associated with Rosacea): Diagnostic and Therapeutic Approaches
DC Field | Value | Language |
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dc.contributor.author | Kim, Jung Eun | - |
dc.contributor.author | Sim, Chang Yoon | - |
dc.contributor.author | Park, A. Young | - |
dc.contributor.author | Hong, Soon Auck | - |
dc.contributor.author | Parke, Young Lip | - |
dc.contributor.author | Jang, Sun Young | - |
dc.contributor.author | Lee, Sung Yul | - |
dc.date.accessioned | 2021-08-11T09:44:27Z | - |
dc.date.available | 2021-08-11T09:44:27Z | - |
dc.date.issued | 2019-04 | - |
dc.identifier.issn | 1013-9087 | - |
dc.identifier.issn | 2005-3894 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/4634 | - |
dc.description.abstract | Morbihan disease (MD) is a rare form of rosacea that presents with chronic erythema and solid oedema on the upper half of the face. A diagnosis of MD can be made only after eliminating diseases that are similar in terms of clinical and histopathological presentation. The cause of MD remains unclear and no standardised treatment is yet available. MD often tends to be recalcitrant to therapies commonly used to treat rosacea, including systemic corticosteroids, antibiotics, isotretinoin, and topical regimens. Thus, surgical interventions have been attempted but most cases have exhibited unsatisfactory responses. We treated six patients with extreme eyelid lymphoedema without any other cutaneous manifestation. Surgical eyelid reduction was performed in all patients, because ptosis and narrowing of the visual field were the major complaints. Histopathological tests revealed various extents of perivascular and perifollicular inflammation, and dermal oedema. After surgery, patients with severe inflammatory cell infiltration (including mast cells) exhibited a tendency toward recurrence. Other patients with severe dermal oedema exhibited better responses to surgical reduction, and thus no recurrence. We propose that MD should be included in the differential diagnosis of persistent, chronic eyelid oedema even if eyelid oedema is the only manifestation; the histological features may aid in the selection of appropriate therapeutic strategies. We suggest that eyelid reduction surgery can be a useful treatment option for MD patients when there is no massive mast cell infiltration. | - |
dc.format.extent | 5 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | 대한피부과학회 | - |
dc.title | Case Series of Morbihan Disease (Extreme Eyelid Oedema Associated with Rosacea): Diagnostic and Therapeutic Approaches | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.5021/ad.2019.31.2.196 | - |
dc.identifier.scopusid | 2-s2.0-85069041983 | - |
dc.identifier.wosid | 000460679200010 | - |
dc.identifier.bibliographicCitation | Annals of Dermatology, v.31, no.2, pp 196 - 200 | - |
dc.citation.title | Annals of Dermatology | - |
dc.citation.volume | 31 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 196 | - |
dc.citation.endPage | 200 | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002447832 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Dermatology | - |
dc.relation.journalWebOfScienceCategory | Dermatology | - |
dc.subject.keywordPlus | LYMPHEDEMA | - |
dc.subject.keywordPlus | PATHOGENESIS | - |
dc.subject.keywordPlus | MINOCYCLINE | - |
dc.subject.keywordAuthor | Edema | - |
dc.subject.keywordAuthor | Eyelids | - |
dc.subject.keywordAuthor | Rosacea | - |
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