Determination of an Optimized Weighting Factor of Liver Parenchyma for Six-point Interference Dixon Fat Percentage Imaging Accuracy in Nonalcoholic Fatty Liver Disease Rat Model
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Onseok | - |
dc.contributor.author | Lee, Suk-Jun | - |
dc.contributor.author | Yu, Seung-Man | - |
dc.date.accessioned | 2021-08-11T11:24:03Z | - |
dc.date.available | 2021-08-11T11:24:03Z | - |
dc.date.issued | 2018-12 | - |
dc.identifier.issn | 1076-6332 | - |
dc.identifier.issn | 1878-4046 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/5480 | - |
dc.description.abstract | Rationale and Objectives: The aim of this study was to determine the optimal weighting factor (WF) for precise quantification using six point interference Dixon fat percentage imaging by analyzing changes in WFs of fatty acid metabolites (FMs) in high-fat-induced fatty liver disease rat model. Materials and Methods: Individual FM-related WFs were calculated based on concentration ratios of integrated areas of seven peak FMs with four phantom series. Ten 8-week-old male Sprague-Dawley rats were used for baseline quantification of fat in liver magnetic resonance imaging or magnetic resonance spectroscopy data. These seven lipid metabolites were then quantitatively analyzed. Spearman test was used for correlation analysis of different lipid proton concentrations. The most accurate WF for six-point interference Dixon fat percentage imaging was then determined. Results: The seven lipid resonance WF values obtained from magnetic resonance spectroscopy data for three different oils (oleic, linoleic, and soybean) were different from each other. In lipid phantoms, except for the phantom containing oleic acid, changes in FP values were significantly different when WFs were changed in six-point interference Dixon fat percentage image. The seven lipid resonance WF values for the nonalcoholic fatty liver animal model were different from human subcutaneous adipose tissue lipid WF values. Conclusions: WF affected the calculation of six-point interference Dixon-based fat percentage imaging value in phantom experiment. If WF of liver parenchyma FM which is specific to each liver disease is applied, the accuracy of six-point interference Dixon fat percentage imaging can be further increased. | - |
dc.format.extent | 8 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Association of University Radiologists | - |
dc.title | Determination of an Optimized Weighting Factor of Liver Parenchyma for Six-point Interference Dixon Fat Percentage Imaging Accuracy in Nonalcoholic Fatty Liver Disease Rat Model | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1016/j.acra.2018.03.029 | - |
dc.identifier.scopusid | 2-s2.0-85047437925 | - |
dc.identifier.wosid | 000452686800014 | - |
dc.identifier.bibliographicCitation | Academic Radiology, v.25, no.12, pp 1595 - 1602 | - |
dc.citation.title | Academic Radiology | - |
dc.citation.volume | 25 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 1595 | - |
dc.citation.endPage | 1602 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.subject.keywordPlus | MAGNETIC-RESONANCE-SPECTROSCOPY | - |
dc.subject.keywordPlus | HEPATIC FAT | - |
dc.subject.keywordPlus | NATURAL-HISTORY | - |
dc.subject.keywordPlus | MR SPECTROSCOPY | - |
dc.subject.keywordPlus | ADIPOSE-TISSUE | - |
dc.subject.keywordPlus | GRADIENT-ECHO | - |
dc.subject.keywordPlus | 3-POINT DIXON | - |
dc.subject.keywordPlus | QUANTIFICATION | - |
dc.subject.keywordPlus | VALIDATION | - |
dc.subject.keywordPlus | WATER | - |
dc.subject.keywordAuthor | MR spectroscopy (MRS) method | - |
dc.subject.keywordAuthor | water fat imaging | - |
dc.subject.keywordAuthor | other MRI-related interventions | - |
dc.subject.keywordAuthor | hepatobiliary | - |
dc.subject.keywordAuthor | other endogenous contrasts | - |
dc.subject.keywordAuthor | spectroscopic imaging | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(31538) 22, Soonchunhyang-ro, Asan-si, Chungcheongnam-do, Republic of Korea+82-41-530-1114
COPYRIGHT 2021 by SOONCHUNHYANG UNIVERSITY ALL RIGHTS RESERVED.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.