The multi-vessel and diffuse coronary spasm is a risk factor for persistent angina in patients received anti-angina medication
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Sang-Ho | - |
dc.contributor.author | Choi, Byoung Geol | - |
dc.contributor.author | Rha, Seung-Woon | - |
dc.contributor.author | Kang, Tae Soo | - |
dc.date.accessioned | 2021-08-11T11:43:26Z | - |
dc.date.available | 2021-08-11T11:43:26Z | - |
dc.date.issued | 2018-11 | - |
dc.identifier.issn | 0025-7974 | - |
dc.identifier.issn | 1536-5964 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/5528 | - |
dc.description.abstract | Coronary artery spasm (CAS) is known to be a risk factor for cardiovascular events. However, there is limited data whether the multi-vessel and diffuse spasm (MVDS) is related to more adverse clinical outcomes compared to the Non-MVDS. The aim of this study is to evaluate the impact of the MVDS on clinical outcomes during a 3-year clinical follow-up period. A total 2797 patients underwent coronary angiography (CAG) with acetylcholine (ACH) provocation test from Nov 2004 to Oct 2010 were enrolled. It is a single-center, observational, prospective, all-comers registry designed to reflect the "real world" practic. The patients were divided into the 3 groups; the negative spasm (NS) group (n = 1188), the Non-MVDS group (n = 1081), and the MVDS group (n = 528). The incidence of major adverse cardiac events (MACE) and recurrent angina was evaluated up to 3 years. To minimize confounding factors, multivariable Cox-proportional hazards regression analysis was performed. In the 3-year clinical follow-up, the incidence of total death, myocardial infarction, de novo percutaneous coronary intervention (PCI), cerebrovascular accident and MACE were similar among the 3 groups. However, recurrent angina occurred more frequently in the MVDS group than in the NS group (hazard ratio [HR], 1.96; 95% confidence interval [CI], 1.27-3.02; P = .002). Recurrence angina between the MVDS group and the Non-MVDS group was not statistically significant (HR, 1.36; 95% CI, 0.91-2.03; P = .129). In this study, although the incidence of major adverse cardiovascular events were not different regardless of spasm type, the MVDS was associated with higher incidence of recurrent chest pain requiring repeat CAG during the 3-year follow-up period, suggesting more intensive optimal medical therapy with close clinical follow up would be necessary for this particular subset of patients. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Lippincott Williams & Wilkins Ltd. | - |
dc.title | The multi-vessel and diffuse coronary spasm is a risk factor for persistent angina in patients received anti-angina medication | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1097/MD.0000000000013288 | - |
dc.identifier.scopusid | 2-s2.0-85056803960 | - |
dc.identifier.wosid | 000452464700040 | - |
dc.identifier.bibliographicCitation | Medicine, v.97, no.47 | - |
dc.citation.title | Medicine | - |
dc.citation.volume | 97 | - |
dc.citation.number | 47 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | ACETYLCHOLINE PROVOCATION TEST | - |
dc.subject.keywordPlus | 3-YEAR FOLLOW-UP | - |
dc.subject.keywordPlus | ARTERY SPASM | - |
dc.subject.keywordPlus | ANGIOGRAPHIC CHARACTERISTICS | - |
dc.subject.keywordPlus | MYOCARDIAL-INFARCTION | - |
dc.subject.keywordPlus | SINGLE-VESSEL | - |
dc.subject.keywordPlus | IMPACT | - |
dc.subject.keywordPlus | MULTIVESSEL | - |
dc.subject.keywordPlus | PROGNOSIS | - |
dc.subject.keywordPlus | DIAGNOSIS | - |
dc.subject.keywordAuthor | acetylcholine provocation test | - |
dc.subject.keywordAuthor | clinical outcomes | - |
dc.subject.keywordAuthor | coronary artery spasm | - |
dc.subject.keywordAuthor | type | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(31538) 22, Soonchunhyang-ro, Asan-si, Chungcheongnam-do, Republic of Korea+82-41-530-1114
COPYRIGHT 2021 by SOONCHUNHYANG UNIVERSITY ALL RIGHTS RESERVED.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.