Complete Versus Culprit-Only Revascularization for ST-Segment Elevation Myocardial Infarction and Multivessel Disease in the 2nd Generation Drug-Eluting Stent Era: Data from the INTERSTELLAR Regisry
- Authors
- Kwon, Sung Woo; Park, Sang-Don; Moon, Jeonggeun; Oh, Pyung Chun; Jang, Ho-Jun; Park, Hyun Woo; Kim, Tae-Noon; Lee, Kyounghoon; Suh, Jon; Kang, WoongChol
- Issue Date
- Nov-2018
- Publisher
- 대한심장학회
- Keywords
- ST elevation myocardial infarction; Percutaneous coronary intervention
- Citation
- Korean Circulation Journal, v.48, no.11, pp 989 - 999
- Pages
- 11
- Journal Title
- Korean Circulation Journal
- Volume
- 48
- Number
- 11
- Start Page
- 989
- End Page
- 999
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/5534
- DOI
- 10.4070/kcj.2017.0387
- ISSN
- 1738-5520
1738-5555
- Abstract
- Background and Objectives: We aimed to compare outcomes of complete revascularization (CR) versus culprit-only revascularization for ST-segment elevation myocardial infarction (STEMI) and multivessel disease (MVD) in the 2nd generation drug-eluting stent (DES) era. Methods: From 2009 to 2014, patients with STEMI and MVD, who underwent primary percutaneous coronary intervention (PCI) using a 2nd generation DES for culprit lesions were enrolled. CR was defined as PCI for a non-infarct-related artery during the index admission. Major adverse cardiovascular event (MACE) was defined as cardiovascular (CV) death, non-fatal myocardial infarction, target lesion revascularization, or heart failure during the follow-up year. Results: In total, 705 MVD patients were suitable for the analysis, of whom 286 (41%) underwent culprit-only PCI and 419 (59%) underwent CR during the index admission. The incidence of MACE was 11.5% in the CR group versus 18.5% in the culprit-only group (hazard ratio [HR], 0.56; 95% confidence interval [CI], 0.37-0.86; p<0.01; adjusted HR, 0.64; 95% CI, 0.40-0.99; p=0.04). The CR group revealed a significantly lower incidence of CV death (7.2% vs. 12.9%; HR, 0.51; 95% CI, 0.31-0.86; p=0.01 and adjusted HR, 0.57; 95% CI; 0.32-0.97; p=0.03, respectively). Conclusions: CR was associated with better outcomes including reductions in MACE and CV death at 1 year of follow-up compared with culprit-only PCI in the 2nd generation DES era.
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Collections - College of Medicine > Department of Internal Medicine > 1. Journal Articles
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