Adding ancillary features to enhancement patterns of hepatocellular carcinoma on gadoxetic acid-enhanced magnetic resonance imaging improves diagnostic performance
DC Field | Value | Language |
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dc.contributor.author | Min, Ji Hye | - |
dc.contributor.author | Kim, Young Kon | - |
dc.contributor.author | Sinn, Dong Hyun | - |
dc.contributor.author | Choi, Seo-Youn | - |
dc.contributor.author | Jeong, Woo Kyoung | - |
dc.contributor.author | Lee, Won Jae | - |
dc.contributor.author | Ha, Sang Yun | - |
dc.contributor.author | Ahn, Soohyun | - |
dc.contributor.author | Kim, Min-Ji | - |
dc.date.accessioned | 2021-08-11T11:43:55Z | - |
dc.date.available | 2021-08-11T11:43:55Z | - |
dc.date.issued | 2018-09 | - |
dc.identifier.issn | 2366-004X | - |
dc.identifier.issn | 2366-0058 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/5678 | - |
dc.description.abstract | To assess the added value of intratumoral ancillary features to conventional enhancement pattern-based diagnosis of hepatocellular carcinoma (HCC) on gadoxetic acid-enhanced magnetic resonance imaging (MRI). A total of 773 consecutive patients with surgically resected 773 primary hepatic tumors (699 HCCs, 63 intrahepatic cholangiocarcinomas, and 11 benign nodules) who underwent gadoxetic acid-enhanced MRI were retrospectively identified. Enhancement patterns and three ancillary features of capsule, septum, and T2 spotty hyperintensity were assessed by two radiologists. Performance of enhancement pattern-based diagnosis of HCC was compared to diagnosis of HCC based on enhancement pattern plus ancillary features. Enhancement patterns were positive (arterial diffuse hyperenhancement with washout) for 562 (72.7%) tumors, negative (no arterial hyperenhancement and no washout) for 75 (9.7%), and inconclusive (either no arterial hyperenhancement or no washout) for 136 (17.6%). Capsule was observed in 498 (64.4%) tumors, septum in 521 (67.3%), and T2 spotty hyperintensity in 107 (13.8%). The accuracy and sensitivity of HCC diagnosis was improved significantly after adding at least one ancillary feature compared with enhancement pattern-based diagnosis of HCCs (79.9% vs. 91.1% for accuracy, p < 0.0001 and 79.1% vs. 92.0% for sensitivity, p < 0.0001) with a minor tradeoff in specificity (87.8% vs. 82.4%, p = 0.125). Adding at least two ancillary features improved accuracy (88.1%, p < 0.0001) and sensitivity (88.1%, p < 0.0001) without changing specificity (87.8%, p = 1.0). Adding intratumoral ancillary features of capsule, septum and T2 spotty hyperintensity to conventional enhancement patterns on gadoxetic acid-enhanced MRI improved accuracy and sensitivity, while maintaining specificity for HCC diagnosis. | - |
dc.format.extent | 12 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Springer New York | - |
dc.title | Adding ancillary features to enhancement patterns of hepatocellular carcinoma on gadoxetic acid-enhanced magnetic resonance imaging improves diagnostic performance | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1007/s00261-018-1480-9 | - |
dc.identifier.scopusid | 2-s2.0-85042358866 | - |
dc.identifier.wosid | 000442351800013 | - |
dc.identifier.bibliographicCitation | Abdominal Radiology, v.43, no.9, pp 2309 - 2320 | - |
dc.citation.title | Abdominal Radiology | - |
dc.citation.volume | 43 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 2309 | - |
dc.citation.endPage | 2320 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.subject.keywordPlus | CLINICAL-PRACTICE GUIDELINES | - |
dc.subject.keywordPlus | HISTOPATHOLOGIC FINDINGS | - |
dc.subject.keywordPlus | HEPATOBILIARY PHASE | - |
dc.subject.keywordPlus | HEPATIC NODULES | - |
dc.subject.keywordPlus | MRI | - |
dc.subject.keywordPlus | CT | - |
dc.subject.keywordPlus | DIFFERENTIATION | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | CIRRHOSIS | - |
dc.subject.keywordPlus | CONTRAST | - |
dc.subject.keywordAuthor | Hepatocellular carcinoma | - |
dc.subject.keywordAuthor | Magnetic resonance imaging | - |
dc.subject.keywordAuthor | Diagnosis | - |
dc.subject.keywordAuthor | Enhancement | - |
dc.subject.keywordAuthor | Ancillary feature | - |
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