EUS-Guided Biliary Drainage Versus ERCP for the Primary Palliation of Malignant Biliary Obstruction: A Multicenter Randomized Clinical Trial
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Paik, Woo Hyun | - |
dc.contributor.author | Lee, Tae Hoon | - |
dc.contributor.author | Park, Do Hyun | - |
dc.contributor.author | Choi, Jun-Ho | - |
dc.contributor.author | Kim, Seon-Ok | - |
dc.contributor.author | Jang, Sunguk | - |
dc.contributor.author | Kim, Dong Uk | - |
dc.contributor.author | Shim, Ju Hyun | - |
dc.contributor.author | Song, Tae Jun | - |
dc.contributor.author | Lee, Sang Soo | - |
dc.contributor.author | Seo, Dong-Wan | - |
dc.contributor.author | Lee, Sung Koo | - |
dc.contributor.author | Kim, Myung-Hwan | - |
dc.date.accessioned | 2021-08-11T12:23:30Z | - |
dc.date.available | 2021-08-11T12:23:30Z | - |
dc.date.issued | 2018-07 | - |
dc.identifier.issn | 0002-9270 | - |
dc.identifier.issn | 1572-0241 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/5838 | - |
dc.description.abstract | OBJECTIVES: The goal of the study was to determine whether endoscopic ultrasound (EUS)-guided biliary drainage (EUS-BD) is comparable to conventional transpapillary stenting with endoscopic retrograde cholangiopancreatography (ERCP) in palliation of malignant distal biliary obstruction. Although ERCP for the palliation of malignant biliary obstruction is the standard of care, post-procedure pancreatitis and stent dysfunctions are not uncommon. While EUS-BD has garnered interest as a viable alternative when ERCP is impossible, its role as a primary palliation of malignant distal biliary obstruction is yet to be proven. METHODS: We performed random allocation to EUS-BD or ERCP in 125 patients with unresectable malignant distal biliary obstruction at four tertiary academic referral centers in South Korea. RESULTS: Technical success rates were 93.8% (60/64) for EUS-BD and 90.2% (55/61) for ERCP (difference 3.6%, 95% 1-sided confidence interval lower limit -4.4%, P = 0.003 for noninferiority margin of 10%). Clinical success rates were 90.0% (54/60) in EUS-BD and 94.5% (52/55) in ERCP (P = 0.49). Lower rates of overall adverse events (6.3% vs 19.7%, P = 0.03) including postprocedure pancreatitis (0 vs 14.8%), reintervention (15.6% vs 42.6%), and higher rate of stent patency (85.1% vs 48.9%) were observed with EUS-BD. EUS-BD was also associated with more preserved quality of life (QOL) than transpapillary stenting after 12 weeks of the procedure. CONCLUSIONS: This study demonstrated comparable technical and clinical success rates between EUS-BD and ERCP in relief of malignant distal biliary obstruction. Substantially longer duration of patency coupled with lower rates of adverse events and reintervention, and more preserved QOL were observed with EUS-BD (cris.nih.go.kr, Identifier: KCT0001396, https://cris.nih.go.kr/cris/search/search_result_st01_en.jsp?seq=9716&ltype=&rtype=). | - |
dc.format.extent | 11 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Blackwell Publishing Inc. | - |
dc.title | EUS-Guided Biliary Drainage Versus ERCP for the Primary Palliation of Malignant Biliary Obstruction: A Multicenter Randomized Clinical Trial | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1038/s41395-018-0122-8 | - |
dc.identifier.scopusid | 2-s2.0-85049217032 | - |
dc.identifier.wosid | 000442487800015 | - |
dc.identifier.bibliographicCitation | American Journal of Gastroenterology, v.113, no.7, pp 987 - 997 | - |
dc.citation.title | American Journal of Gastroenterology | - |
dc.citation.volume | 113 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 987 | - |
dc.citation.endPage | 997 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.subject.keywordPlus | ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY | - |
dc.subject.keywordPlus | METAL STENT PLACEMENT | - |
dc.subject.keywordPlus | PANCREATIC-CANCER | - |
dc.subject.keywordPlus | ADVERSE EVENTS | - |
dc.subject.keywordPlus | TRACT OBSTRUCTION | - |
dc.subject.keywordPlus | SURGICAL BYPASS | - |
dc.subject.keywordPlus | FAILED ERCP | - |
dc.subject.keywordPlus | CHOLEDOCHODUODENOSTOMY | - |
dc.subject.keywordPlus | PREVENTION | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordAuthor | 의약학 | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(31538) 22, Soonchunhyang-ro, Asan-si, Chungcheongnam-do, Republic of Korea+82-41-530-1114
COPYRIGHT 2021 by SOONCHUNHYANG UNIVERSITY ALL RIGHTS RESERVED.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.