Disseminated Superficial Actinic Porokeratosis in a Patient with Psoriasis, after Long-Term Narrowband Ultraviolet B Phototherapy
- Authors
- Sim, Chang Yoon; Shin, Ji Yeoun; Lee, Sung Yul; Park, Young Lip
- Issue Date
- Apr-2018
- Publisher
- 대한피부과학회
- Keywords
- Porokeratosis; Psoriasis; Ultraviolet therapy
- Citation
- Annals of Dermatology, v.30, no.2, pp 211 - 213
- Pages
- 3
- Journal Title
- Annals of Dermatology
- Volume
- 30
- Number
- 2
- Start Page
- 211
- End Page
- 213
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/6073
- DOI
- 10.5021/ad.2018.30.2.211
- ISSN
- 1013-9087
2005-3894
- Abstract
- Porokeratosis is a rare epidermal disorder characterized by annular or linear hyperkeratotic plaques with slightly raised thread-like borders, and in most cases, atrophic centers. Disseminated superficial porokeratosis and disseminated superficial actinic porokeratosis (DSAP), which primarily involve sun-exposed areas, are common types of porokeratoses. Histologically, a column of parakeratotic cells, a so-called cornoid lamella, is a hallmark of porokeratosis. Porokeratosis is considered to result from the inability to eliminate an abnormal keratinocyte clone induced by genetic factors and various stimuli, including sunlight, artificial ultraviolet light, viral infections, immunosuppressive conditions (hematologic malignancies, organ transplants, or autoimm une disease), and immunosuppressive therapies. Here, we report a 59-year-old Korean woman with DSAP that developed after narrowband ultraviolet B (NB-UVB) therapy for psoriasis. Our case emphasizes the occurrence of DSAP due to NB-UVB that is able to induce local immunosuppression at the irradiated site; the pathogenesis of DSAP remains unclear.
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Collections - College of Medicine > Department of Dermatology > 1. Journal Articles
- College of Medicine > Department of Dermatology > 1. Journal Articles
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