Nonalcoholic Fatty Liver Disease and Abdominal Fat Accumulation According to Vitamin D Status in Patients with Type 2 Diabetes
DC Field | Value | Language |
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dc.contributor.author | Choi, Dug-Hyun | - |
dc.contributor.author | Jung, Chan-Hee | - |
dc.contributor.author | Mok, Ji-Oh | - |
dc.contributor.author | Kim, Chul-Hee | - |
dc.contributor.author | Kang, Sung Koo | - |
dc.contributor.author | Kim, Bo-Yeon | - |
dc.date.accessioned | 2021-08-11T12:43:37Z | - |
dc.date.available | 2021-08-11T12:43:37Z | - |
dc.date.issued | 2018-03 | - |
dc.identifier.issn | 2508-6235 | - |
dc.identifier.issn | 2508-7576 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/6191 | - |
dc.description.abstract | Background: Vitamin D deficiency is known to increase the incidence of metabolic syndrome. Nonalcoholic fatty liver disease is a common metabolic disease in patients with type 2 diabetes. This study evaluated nonalcoholic fatty liver disease and abdominal fat accumulation according to 25-hydroxyvitamin D status in patients with type 2 diabetes. Methods: The study comprised 302 patients with type 2 diabetes. Patients were divided into three groups based upon their 25-hydroxyvitamin D status: vitamin D deficient group (< 10 ng/mL), vitamin D insufficient group (>= 10 to < 20 ng/mL) and vitamin D sufficient group (>= 20 ng/mL). Patient clinical and laboratory markers were evaluated retrospectively. Results: Visceral fat thickness was significantly higher in the vitamin D deficient group. There were no differences in glycemic control, body mass index, and subcutaneous fat thickness correlated with 25-hydroxyvitamin D status. The prevalence of nonalcoholic fatty liver disease was significantly higher in the vitamin D deficient group compared to the vitamin D sufficient and vitamin D insufficient groups. In multivariate logistic analysis, after adjustment for age, sex, body mass index, glycated hemoglobin and homeostasis model assessment of insulin resistance, patients with type 2 diabetes in the vitamin D sufficient group showed significantly lower odds ratio for nonalcoholic fatty liver disease than those within the vitamin D deficient group. Conclusion: In type 2 diabetes, the vitamin D deficient group showed thicker visceral fat thickness and higher nonalcoholic fatty liver disease prevalence. | - |
dc.format.extent | 8 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | 대한비만학회 | - |
dc.title | Nonalcoholic Fatty Liver Disease and Abdominal Fat Accumulation According to Vitamin D Status in Patients with Type 2 Diabetes | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.7570/jomes.2018.27.1.53 | - |
dc.identifier.wosid | 000461764500007 | - |
dc.identifier.bibliographicCitation | Journal of Obesity & Metabolic Syndrome, v.27, no.1, pp 53 - 60 | - |
dc.citation.title | Journal of Obesity & Metabolic Syndrome | - |
dc.citation.volume | 27 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 53 | - |
dc.citation.endPage | 60 | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002329226 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Endocrinology & Metabolism | - |
dc.relation.journalWebOfScienceCategory | Endocrinology & Metabolism | - |
dc.subject.keywordPlus | SERUM 25-HYDROXYVITAMIN D | - |
dc.subject.keywordPlus | INSULIN-RESISTANCE | - |
dc.subject.keywordPlus | METABOLIC SYNDROME | - |
dc.subject.keywordPlus | HYPOVITAMINOSIS-D | - |
dc.subject.keywordPlus | NATIONAL-HEALTH | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | ASSOCIATION | - |
dc.subject.keywordPlus | PREVALENCE | - |
dc.subject.keywordPlus | MORTALITY | - |
dc.subject.keywordPlus | OBESITY | - |
dc.subject.keywordAuthor | Non-alcoholic fatty liver disease | - |
dc.subject.keywordAuthor | Vitamin D | - |
dc.subject.keywordAuthor | Type 2 diabetes mellitus | - |
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