Small-animal PET imaging analysis with [F-18]FHBG in a mouse model of HSV1-tk gene expression in melanoma
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Onseok | - |
dc.contributor.author | Kim, Jaeyoung | - |
dc.contributor.author | Oh, Chilhwan | - |
dc.date.accessioned | 2021-08-11T12:43:46Z | - |
dc.date.available | 2021-08-11T12:43:46Z | - |
dc.date.issued | 2018-02 | - |
dc.identifier.issn | 0906-6705 | - |
dc.identifier.issn | 1600-0625 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/6236 | - |
dc.description.abstract | The purpose of this study was to establish a small-animal model for molecular imaging and to acquire basic data on assessing the efficacy of candidate melanoma drugs using small-animal PET imaging analysis with [F-18]FHBG for herpes simplex virus 1-thymidine kinase (HSV1-tk) gene expression in a melanoma mouse model. The B16 melanoma cell line was transduced with a recombinant lentiviral vector containing the HSV1-tk gene and inoculated into the back skin of C57BL/6J mice. [F-18]FHBG PET imaging showed better contrast for HSV1-tk(+) melanomas compared to brain, heart, gall bladder, intestine and kidney than did [F-18]FDG PET imaging. | - |
dc.format.extent | 3 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Blackwell Publishing Inc. | - |
dc.title | Small-animal PET imaging analysis with [F-18]FHBG in a mouse model of HSV1-tk gene expression in melanoma | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1111/exd.13475 | - |
dc.identifier.scopusid | 2-s2.0-85041109192 | - |
dc.identifier.wosid | 000423679700015 | - |
dc.identifier.bibliographicCitation | Experimental Dermatology, v.27, no.2, pp 199 - 201 | - |
dc.citation.title | Experimental Dermatology | - |
dc.citation.volume | 27 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 199 | - |
dc.citation.endPage | 201 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Dermatology | - |
dc.relation.journalWebOfScienceCategory | Dermatology | - |
dc.subject.keywordPlus | LIVING MICE | - |
dc.subject.keywordPlus | REPORTER | - |
dc.subject.keywordAuthor | [F-18]FDG | - |
dc.subject.keywordAuthor | [F-18]FHBG | - |
dc.subject.keywordAuthor | HSV1-tk | - |
dc.subject.keywordAuthor | lentiviral vector | - |
dc.subject.keywordAuthor | melanoma | - |
dc.subject.keywordAuthor | small-animal PET | - |
dc.subject.keywordAuthor | CT | - |
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