소아청소년의 중등도/중증 폐쇄수면무호흡증후군의 예측인자로서 혈액 표지자
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김승수 | - |
dc.contributor.author | 양광익 | - |
dc.date.accessioned | 2021-08-11T13:23:55Z | - |
dc.date.available | 2021-08-11T13:23:55Z | - |
dc.date.created | 2021-06-17 | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 2384-2423 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/6627 | - |
dc.description.abstract | Objectives: We conducted this study to evaluate the diagnostic value of hematologic markers for moderate to severe obstructive sleep apnea syndrome (OSAS). Methods: We performed the study using medical records from our sleep disorders center. We collected information regarding obstructive apnea-hypopnea index (oAHI), age, sex, body mass index, and complete blood counts with differential counts [white blood cell (WBC) count, neutrophil count, lymphocyte count, red blood cell distribution width (RDW), mean platelet volume, platelet count, platelet distribution width (PDW), neutrophil-lymphocyte ratio, and platelet- lymphocyte ratio]. We excluded patients who were younger than 2 years, older than 14 years, obese/underweight, and those who had a hematologic or severe medical illness. Results: We assessed records from 57 patients (7.98±3.25 years old, 35 men). We classified the subjects into three groups based on their oAHI scores, as follows: normal (oAHI<1), mild OSAS (1≤oAHI<5), and moderate/severe OSAS (oAHI≥5). Using a multivariate multinomial logistic regression model (pseudo R2=0.33), we found significant differences among the groups in RDW [moderate/severe OSAS vs. mild OSAS, adjusted odds ratio (OR): 8.77, p-value: 0.03], PDW (mild OSAS vs. normal, adjusted OR: 1.05, p-value: 0.04), and WBC (moderate/severe OSAS vs. normal, adjusted OR: 1.42, p-value: 0.03). Conclusions: RDW, PDW, and WBC had diagnostic value for moderate/severe OSAS in our study. Further prospective and validation studies are required to develop a screening tool for moderate/severe OSAS in children and adolescents. | - |
dc.language | 한국어 | - |
dc.language.iso | ko | - |
dc.publisher | 대한수면연구학회 | - |
dc.title | 소아청소년의 중등도/중증 폐쇄수면무호흡증후군의 예측인자로서 혈액 표지자 | - |
dc.title.alternative | Hematologic Markers as a Predictive Factor for Moderate to Severe Obstructive Sleep Apnea Syndrome in Children and Adolescents | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | 김승수 | - |
dc.contributor.affiliatedAuthor | 양광익 | - |
dc.identifier.doi | 10.13078/jsm.18008 | - |
dc.identifier.bibliographicCitation | Journal of sleep medicine, v.15, no.1, pp.20 - 26 | - |
dc.relation.isPartOf | Journal of sleep medicine | - |
dc.citation.title | Journal of sleep medicine | - |
dc.citation.volume | 15 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 20 | - |
dc.citation.endPage | 26 | - |
dc.type.rims | ART | - |
dc.identifier.kciid | ART002362869 | - |
dc.description.journalClass | 2 | - |
dc.description.journalRegisteredClass | kci | - |
dc.subject.keywordAuthor | Children | - |
dc.subject.keywordAuthor | Sleep apnea syndrome | - |
dc.subject.keywordAuthor | Red cell distribution width | - |
dc.subject.keywordAuthor | Platelet distribution width. | - |
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