Clinical Features and Risk Factors of Herpes Zoster Ophthalmicus
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Mun, Chi Young | - |
dc.contributor.author | Jung, Moon Sun | - |
dc.date.accessioned | 2021-08-11T14:23:50Z | - |
dc.date.available | 2021-08-11T14:23:50Z | - |
dc.date.issued | 2017-12 | - |
dc.identifier.issn | 0378-6471 | - |
dc.identifier.issn | 2092-9374 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/7022 | - |
dc.description.abstract | Purpose: To evaluate the clinical characteristics and risk factors of severe manifestation of herpes zoster ophthalmicus. Methods: We conducted a retrospective analysis using medical records from 106 patients diagnosed with herpes zoster ophthalmicus from January 2012 to June 2015. Patients were classified according to the type and frequency of ophthalmologic manifestations. Patients with conjunctivitis, punctate keratitis, and pseudodendritic keratitis were classified into the mild group, whereas patients with deep stromal keratitis, endothelitis, scleritis, glaucoma, and extraocular muscle paralysis were classified into the severe group. The age, sex, severity, location of skin lesions, delayed time to treatment, the presence of Hutchinson's sign, and associated systemic diseases were compared between the groups. In addition, we investigated changes in vision, intraocular pressure, treatment duration, recurrence and the prevalence of postherpetic neuralgia. Results: The incidence of conjunctivitis (47.2%), punctate keratitis (42.5%), pseudodendritic keratitis (12.2%), deep stromal keratitis (12.2%), endothelitis (15.1%), scleritis (18.9%), glaucoma (14.2%), and extraocular muscle (EOM) paralysis (4.7%) were observed in these patients. The group with mild disease included 70 cases with conjunctivitis, punctate keratitis and pseudodendritic keratitis. The severe group included 36 cases with deep stromal keratitis, endothelitis, scleritis, glaucoma and EOM palsy. Disease most often occurred in the distribution of the first branch of the trigeminal nerve, with no differences in the age or sex of patients in both groups. Severe manifestations were more common when a greater extent of the skin was involved, when Hutchinson's sign was present, or when treatment was significantly delayed. There were no significant differences between the two groups in recurrence or the presence of postherpetic neuralgia. Conclusion: Long-term treatment for herpes zoster opthalmicus is more likely to be required if severe manifestation of disease exists, such as widespread skin involvement, Hutchinson's sign, or a delay to the initiation of antiviral treatment. More active observation and treatment are required in such cases. | - |
dc.format.extent | 8 | - |
dc.language | 한국어 | - |
dc.language.iso | KOR | - |
dc.publisher | 대한안과학회 | - |
dc.title | Clinical Features and Risk Factors of Herpes Zoster Ophthalmicus | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.3341/jkos.2017.58.12.1317 | - |
dc.identifier.wosid | 000471823800001 | - |
dc.identifier.bibliographicCitation | 대한안과학회지, v.58, no.12, pp 1317 - 1324 | - |
dc.citation.title | 대한안과학회지 | - |
dc.citation.volume | 58 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 1317 | - |
dc.citation.endPage | 1324 | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002290942 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Ophthalmology | - |
dc.relation.journalWebOfScienceCategory | Ophthalmology | - |
dc.subject.keywordAuthor | Herpes zoster ophthalmicus | - |
dc.subject.keywordAuthor | Hutchinson's sign | - |
dc.subject.keywordAuthor | Ocular manifestation | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(31538) 22, Soonchunhyang-ro, Asan-si, Chungcheongnam-do, Republic of Korea+82-41-530-1114
COPYRIGHT 2021 by SOONCHUNHYANG UNIVERSITY ALL RIGHTS RESERVED.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.