The value of gadoxetic acid-enhanced MRI for differentiation between hepatic microabscesses and metastases in patients with periampullary cancer
- Authors
- Choi, Seo-Youn; Kim, Young Kon; Min, Ji Hye; Cha, Dong Ik; Jeong, Woo Kyoung; Lee, Won Jae
- Issue Date
- Oct-2017
- Publisher
- Springer Verlag
- Keywords
- Liver; MRI; Abscess; Neoplasm metastasis; Contrast media; Hepatocyte-specific contrast
- Citation
- European Radiology, v.27, no.10, pp 4383 - 4393
- Pages
- 11
- Journal Title
- European Radiology
- Volume
- 27
- Number
- 10
- Start Page
- 4383
- End Page
- 4393
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/7184
- DOI
- 10.1007/s00330-017-4782-3
- ISSN
- 0938-7994
1432-1084
- Abstract
- We aimed to identify features that differentiate hepatic microabscess from hepatic metastasis on gadoxetic acid-enhanced MRI in patients with periampullary cancer. We included 72 patients (31 patients with 83 hepatic microabscesses and 41 patients with 71 hepatic metastases) who had a history of periampullary cancer and underwent gadoxetic acid-enhanced MRI. Image analysis was performed for margin, signal intensity, rim enhancement, perilesional hyperaemia, pattern on DWI and dynamic phases, and size discrepancy between sequences by consensus of two observers. Multivariate analysis revealed that the following significant parameters favour microabscess: a history of bile duct cancer, perilesional hyperaemia, persistent arterial rim enhancement through the transitional phase (TP), and size discrepancy between T1WI and T2WI and between T1WI and hepatobiliary phase image (HBPI). The diagnostic accuracy for microabscess was highest (90.9%) when showing a size discrepancy ae<yen>30% between T1WI and HBPI or persistent arterial rim enhancement through the TP. When the lesion was positive for both these variables, specificity reached 100%. The combination of a size discrepancy between T1WI and HBPI and persistent arterial rim enhancement through the TP represents a reliable MRI feature for distinguishing between hepatic microabscess and metastasis in patients with periampullary cancer. aEuro cent Gadoxetic acid-enhanced MRI is useful for distinguishing hepatic microabscess from metastasis. aEuro cent Hepatic microabscess showed significant size discrepancy ae<yen>30% between T1WI and HBPI. aEuro cent Arterial rim enhancement persistent through the TP indicates hepatic microabscess.
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Collections - College of Medicine > Department of Radiology > 1. Journal Articles
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