CT, MRI, and F-18-FDG PET/CT findings of malignant peripheral nerve sheath tumor of the head and neck
- Authors
- Kim, Ha Youn; Hwang, Ji Young; Kim, Hyung-Jin; Kim, Yi Kyung; Cha, Jihoon; Park, Gyeong Min; Kim, Sung Tae
- Issue Date
- Oct-2017
- Publisher
- Taylor & Francis
- Keywords
- Head/neck; malignant peripheral nerve sheath tumor (MPSNT); computed tomography (CT); magnetic resonance imaging (MRI); positron emission tomography (PET)
- Citation
- Acta Radiologica, v.58, no.10, pp 1222 - 1230
- Pages
- 9
- Journal Title
- Acta Radiologica
- Volume
- 58
- Number
- 10
- Start Page
- 1222
- End Page
- 1230
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/7198
- DOI
- 10.1177/0284185116684674
- ISSN
- 0284-1851
1600-0455
- Abstract
- Background: Malignant peripheral nerve sheath tumor (MPNST) is a highly malignant tumor and rarely occurs in the head and neck. Purpose: To describe the imaging features of MPNST of the head and neck. Material and Methods: We retrospectively analyzed computed tomography (CT; n = 14), magnetic resonance imaging (MRI; n = 16), and F-18-FDG PET/CT (n = 5) imaging features of 18 MPNSTs of the head and neck in 17 patients. Special attention was paid to determine the nerve of origin from which the tumor might have arisen. Results: All lesions were well-defined (n = 3) or ill-defined (n = 15) masses (mean, 6.1 cm). Lesions were at various locations but most commonly the neck (n = 8), followed by the intracranial cavity (n = 3), paranasal sinus (n = 2), and orbit (n = 2). The nerve of origin was inferred for 11 lesions: seven in the neck, two in the orbit, one in the cerebellopontine angle, and one on the parietal scalp. Attenuation, signal intensity, and enhancement pattern of the lesions on CT and MRI were non-specific. Necrosis/hemorrhage/cystic change within the lesion was considered to be present on images in 13 and bone change in nine. On F-18-FDG PET/CT images, all five lesions demonstrated various hypermetabolic foci with maximum standard uptake value (SUVmax) from 3.2 to 14.6 (mean, 7.16 +/- 4.57). Conclusion: MPNSTs can arise from various locations in the head and neck. Though non-specific, a mass with an illdefined margin along the presumed course of the cranial nerves may aid the diagnosis of MPSNT in the head and neck.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of Medicine > Department of Radiology > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/7198)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.