The Effects of Urinary Albumin and Hypertension on All-Cause and Cardiovascular Disease Mortality in Korea
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Seo, Mi Hae | - |
dc.contributor.author | Lee, Jong-Young | - |
dc.contributor.author | Ryu, Seungho | - |
dc.contributor.author | Won, Yu Sam | - |
dc.contributor.author | Sung, Ki Chul | - |
dc.date.accessioned | 2021-08-11T14:43:47Z | - |
dc.date.available | 2021-08-11T14:43:47Z | - |
dc.date.issued | 2017-08 | - |
dc.identifier.issn | 0895-7061 | - |
dc.identifier.issn | 1941-7225 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/7340 | - |
dc.description.abstract | BACKGROUND Urinary albumin levels and hypertension (HTN) are independently associated with an increased risk of all-cause mortality. The effect of albuminuria on mortality in the absence or presence of HTN is uncertain. This study aimed to evaluate the effect of albuminuria and HTN on all-cause and cardiovascular disease (CVD) mortality. METHODS Mortality outcomes for 32,653 Koreans enrolled in a health screening including measurements of the urinary albumin/creatinine ratio (UACR) at baseline and median follow-up of 5.13 years. Receiver operating characteristic curve analyses were performed in UACR and the cut-point was 5.42 mg/g. The participants for UACR at the cut-point of 5.42 mu g/mg were categorized into UACR < 5.42 or UACR >= 5.42. HTN status was categorized as No HTN or HTN (defined as the absence or presence HTN). RESULTS The median (interquartile) baseline UACRs were higher in those who died than in survivors. Subjects with a UACR >= 5.42 mg/g without or with HTN showed a similar increased risk for all-cause mortality and CVD mortality, even after adjusting for known CVD risk factors compared to those with no HTN/UACR < 5.42 (reference), (all-cause mortality; hazard ratio [HR] 1.48; 95% confidence interval [CI] 1.02-2.15: HR 1.47; 95% CI 0.94-2.32, respectively), (CVD mortality; HR 5.75; 95% CI 1.54-21.47: HR 5.87; 95% CI 1.36-25.29) CONCLUSIONS The presence of urinary albumin and HTN is a significant determinant of CVD and death. Urinary albumin might be more attributable to CVD and all-cause mortality than HTN. | - |
dc.format.extent | 9 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Oxford University Press | - |
dc.title | The Effects of Urinary Albumin and Hypertension on All-Cause and Cardiovascular Disease Mortality in Korea | - |
dc.type | Article | - |
dc.publisher.location | 영국 | - |
dc.identifier.doi | 10.1093/ajh/hpx051 | - |
dc.identifier.scopusid | 2-s2.0-85026439657 | - |
dc.identifier.wosid | 000409078100011 | - |
dc.identifier.bibliographicCitation | American Journal of Hypertension, v.30, no.8, pp 799 - 807 | - |
dc.citation.title | American Journal of Hypertension | - |
dc.citation.volume | 30 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 799 | - |
dc.citation.endPage | 807 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Peripheral Vascular Disease | - |
dc.subject.keywordPlus | LOW-GRADE ALBUMINURIA | - |
dc.subject.keywordPlus | ENDOTHELIAL DYSFUNCTION | - |
dc.subject.keywordPlus | GENERAL-POPULATION | - |
dc.subject.keywordPlus | HEART-FAILURE | - |
dc.subject.keywordPlus | RENAL-DISEASE | - |
dc.subject.keywordPlus | RISK-FACTORS | - |
dc.subject.keywordPlus | MICROALBUMINURIA | - |
dc.subject.keywordPlus | ASSOCIATION | - |
dc.subject.keywordPlus | INDIVIDUALS | - |
dc.subject.keywordPlus | EXCRETION | - |
dc.subject.keywordAuthor | all-cause mortality | - |
dc.subject.keywordAuthor | blood pressure | - |
dc.subject.keywordAuthor | cardiovascular disease mortality | - |
dc.subject.keywordAuthor | hypertension | - |
dc.subject.keywordAuthor | urinary albumin | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(31538) 22, Soonchunhyang-ro, Asan-si, Chungcheongnam-do, Republic of Korea+82-41-530-1114
COPYRIGHT 2021 by SOONCHUNHYANG UNIVERSITY ALL RIGHTS RESERVED.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.