Predictive Factors for Complete Response and Recurrence after Transarterial Chemoembolization in Hepatocellular Carcinoma
DC Field | Value | Language |
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dc.contributor.author | Jeong, Shin Ok | - |
dc.contributor.author | Kim, Eui Bae | - |
dc.contributor.author | Jeong, Soung Won | - |
dc.contributor.author | Jang, Jae Young | - |
dc.contributor.author | Lee, Sae Hwan | - |
dc.contributor.author | Kim, Sang Gyune | - |
dc.contributor.author | Cha, Sang Woo | - |
dc.contributor.author | Kim, Young Seok | - |
dc.contributor.author | Cho, Young Deok | - |
dc.contributor.author | Kim, Hong Soo | - |
dc.contributor.author | Kim, Boo Sung | - |
dc.contributor.author | Kim, Yong Jae | - |
dc.contributor.author | Goo, Dong Erk | - |
dc.contributor.author | Park, Su Yeon | - |
dc.date.accessioned | 2021-08-11T15:23:53Z | - |
dc.date.available | 2021-08-11T15:23:53Z | - |
dc.date.issued | 2017-05 | - |
dc.identifier.issn | 1976-2283 | - |
dc.identifier.issn | 2005-1212 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/7624 | - |
dc.description.abstract | Background/Aims: To investigate the predictive factors for complete response (CR) and recurrence after CR in patients with hepatocellular carcinoma (HCC) treated with transarterial chemoembolization (TACE). Methods: Among 691 newly diagnosed HCC patients, 287 were treated with TACE as a first therapy. We analyzed the predictive factors for CR, recurrence after CR, and overall survival (OS). Results: Eighty-one patients (28.2%) achieved CR after TACE, and recurrence after CR was detected in 35 patients (43.2%). In multivariate analyses, tumor size (<= 5 cm) and single nodularity were predictive factors for CR, with hazard ratios (HRs) of 0.35 (p=0.002) and 0.41 (p < 0.001), respectively. Elevated serum a-fetoprotein (AFP) (> 20 ng/mL) level and multinodularity exhibited significant relationships with recurrence after CR, with HRs of 2.220 (p=0.026) and 3.887 (p < 0.001), respectively. Tumor size (> 5 cm), multinodularity, elevated serum AFP (> 20 ng/mL) level, Child-Turcotte-Pugh score (B and C), and portal vein thrombosis were significant factors for OS. Conclusions: In patients treated with TACE as a first therapy, tumor size (<= 5 cm) and single nodularity were predictive factors for CR, and multinodularity and elevated serum AFP (> 20 ng/mL) levels were predictive factors for recurrence after CR. These factors were also significant for OS. | - |
dc.format.extent | 8 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | 거트앤리버 발행위원회 | - |
dc.title | Predictive Factors for Complete Response and Recurrence after Transarterial Chemoembolization in Hepatocellular Carcinoma | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.5009/gnl16001 | - |
dc.identifier.scopusid | 2-s2.0-85018780206 | - |
dc.identifier.wosid | 000401651100015 | - |
dc.identifier.bibliographicCitation | Gut and Liver, v.11, no.3, pp 409 - 416 | - |
dc.citation.title | Gut and Liver | - |
dc.citation.volume | 11 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 409 | - |
dc.citation.endPage | 416 | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002224193 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.subject.keywordPlus | RISK-FACTORS | - |
dc.subject.keywordPlus | LOCAL RECURRENCE | - |
dc.subject.keywordPlus | ABLATION | - |
dc.subject.keywordPlus | LIVER | - |
dc.subject.keywordPlus | THERAPY | - |
dc.subject.keywordPlus | HCC | - |
dc.subject.keywordAuthor | Carcinoma | - |
dc.subject.keywordAuthor | hepatocellular | - |
dc.subject.keywordAuthor | Chemoembolization | - |
dc.subject.keywordAuthor | therapeutic | - |
dc.subject.keywordAuthor | Complete response | - |
dc.subject.keywordAuthor | Recurrence | - |
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