Preoperative Lymph Node Staging by FDG PET/CT With Contrast Enhancement for Thyroid Cancer: A Multicenter Study and Comparison With Neck CT
DC Field | Value | Language |
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dc.contributor.author | Chong, Ari | - |
dc.contributor.author | Ha, Jung-Min | - |
dc.contributor.author | Han, Yeon-Hee | - |
dc.contributor.author | Kong, Eunjung | - |
dc.contributor.author | Choi, Yunjung | - |
dc.contributor.author | Hong, Ki Hwan | - |
dc.contributor.author | Park, Jun-Hee | - |
dc.contributor.author | Kim, Sung Hoon | - |
dc.contributor.author | Park, Jung Mi | - |
dc.date.accessioned | 2021-08-11T15:24:22Z | - |
dc.date.available | 2021-08-11T15:24:22Z | - |
dc.date.issued | 2017-03 | - |
dc.identifier.issn | 1976-8710 | - |
dc.identifier.issn | 2005-0720 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/7772 | - |
dc.description.abstract | Objectives. The purpose of this study was to compare lymph node (LN) staging using F-18-fluorodeoxyglucose (PUG) positron emission tomography/computed tomography (PET/CT) with contrast-enhancement (CE) PET/CT and contrast enhanced neck CT (neck CT) in patients with thyroid cancer with level-by-level comparison with various factors. Methods. This was a retrospective multicenter study. A total of 85 patients were enrolled. Patients who underwent a preoperative evaluation by CE PET/CT and neck CT for thyroid cancer were enrolled. The gold standard for LN was the combination of surgical pathology and clinical follow-up. We compared CE PET/CT with neck CT using a level-by-level method. Factors, including age, sex, camera, arm position, tumor size, extra-thyroidal extension, tumor location, number of primary tumors, primary tumor maximum standardized uptake value, and the interval from scan to operation were also analyzed. Results. Overall accuracy was 81.2% for CE PET/CT and 68.2% for neck CT. CE PET/CT was more sensitive than neck CT (65.8% vs. 44.7%). Also, CE PET/CT showed higher negative predictive value (77.2% vs. 66.1%). CE PET/CT showed good agreement with the gold standard (weighted kappa [kappa], 0.7) for differentiating NO, N1a, and N1b, whereas neck CT showed moderate agreement (weighted kappa, 0.5). CE PET/CT showed better agreement for the number of levels involved with the gold standard (weighted x, 0.7) than that of neck CT with the gold standard (weighted kappa, 0.5). The accuracies for differentiating NO, N1a, and N1b were 81.2% for CE PET/CT and 68.2% for neck CT. Level-by-level analysis showed that CE PET/CT was more sensitive and has higher negative predictive value for detecting ipsilateral level IV and level VI LNs than neck CT. Other analyzed factors were not related to accuracies of both modalities. Conclusion. CE PET/CT was more sensitive and reliable than neck CT for preoperative LN staging in patients with thyroid cancer. | - |
dc.format.extent | 8 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | 대한이비인후과학회 | - |
dc.title | Preoperative Lymph Node Staging by FDG PET/CT With Contrast Enhancement for Thyroid Cancer: A Multicenter Study and Comparison With Neck CT | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.21053/ceo.2015.01424 | - |
dc.identifier.scopusid | 2-s2.0-85012070393 | - |
dc.identifier.wosid | 000395959000014 | - |
dc.identifier.bibliographicCitation | Clinical and Experimental Otorhinolaryngology, v.10, no.1, pp 121 - 128 | - |
dc.citation.title | Clinical and Experimental Otorhinolaryngology | - |
dc.citation.volume | 10 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 121 | - |
dc.citation.endPage | 128 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Otorhinolaryngology | - |
dc.relation.journalWebOfScienceCategory | Otorhinolaryngology | - |
dc.subject.keywordPlus | CARCINOMA | - |
dc.subject.keywordPlus | TOMOGRAPHY | - |
dc.subject.keywordPlus | METASTASIS | - |
dc.subject.keywordPlus | ULTRASOUND | - |
dc.subject.keywordPlus | DIAGNOSIS | - |
dc.subject.keywordPlus | ACCURACY | - |
dc.subject.keywordAuthor | Positron-Emission Tomography | - |
dc.subject.keywordAuthor | Fluorodeoxyglucose F18 | - |
dc.subject.keywordAuthor | Computed Tomography | - |
dc.subject.keywordAuthor | Thyroid Neoplasms | - |
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