자가면역 뇌염에서 코르티코스테로이드 치료Corticosteroid Treatment in Autoimmune Encephalitis
- Other Titles
- Corticosteroid Treatment in Autoimmune Encephalitis
- Authors
- 선우준상
- Issue Date
- 2017
- Publisher
- 대한신경집중치료학회
- Keywords
- Autoimmune diseases of the nervous system; Immunotherapy; Glucocorticoids; Autoantibodies
- Citation
- Journal of Neurocritical Care, v.10, no.2, pp 60 - 68
- Pages
- 9
- Journal Title
- Journal of Neurocritical Care
- Volume
- 10
- Number
- 2
- Start Page
- 60
- End Page
- 68
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/7949
- DOI
- 10.18700/jnc.170029
- ISSN
- 2005-0348
2508-1349
- Abstract
- An increasing number of neuronal autoantibodies which target cell surface or synaptic proteins have been discovered over the last decade. Autoimmune encephalitis refers to this new category of autoimmune-mediated neurological disorders, which involve the central nervous system. Recent studies have established that autoimmune encephalitis is now the major cause of encephalitis, which was previously considered to be encephalitis of an unknown etiology. Moreover, the fact that autoimmune encephalitis is potentially treatable with immunomodulating therapy has changed the paradigm for the diagnosis and treatment of acute encephalitis syndrome. We herein review the pathophysiology, clinical manifestations, diagnosis, and treatment of autoimmune encephalitis with a focus on corticosteroid therapy as the first-line immunotherapy. In addition, regarding the diagnostic approach, we emphasize the differentiation between autoimmune and infectious encephalitis, because this distinction is not necessarily clear-cut in real clinical practice and should be considered when determining the initiation and type of immunotherapy
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of Medicine > Department of Neurology > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.