Cell Therapy Products in Alzheimer Disease

Abstract

We are rapidly becoming an aging society, with the ongoing increase in challenges of the elderly. The age-related cognitivedecline in accordance with aging society is of major importance in public health. Recent studies have proved the impacts of sexsteroidhormone on the brain; compliant with aging, menopause and decrease in estrogen have an effect on the occurrenceand prevention of Alzheimer’s disease. A new hypothesis states that Alzheimer’s disease is a postmenopausal dementia, andis a negative form of estrogen deficiency. In this review article, we reckoned the cause of postmenopausal Alzheimer’s disease. We further investigated new cell therapies for postmenopausal Alzheimer’s disease, which are under development in somepharmaceutical companies. One remedy is cell therapy that inhibits the amyloid beta formation, and the other is the umbilical cordblood derived mesenchymal stem cell therapy. (J Menopausal Med 2017;23:1-4)