Cerebrospinal Fluid Pressure and Trans-lamina Cribrosa Pressure Difference in Open-angle Glaucoma: KNHANES V
DC Field | Value | Language |
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dc.contributor.author | Kim, Yoon Kyung | - |
dc.contributor.author | Tumurbaatar, Undarmaa | - |
dc.contributor.author | Ohn, Young-Hoon | - |
dc.contributor.author | Ha, Seung Joo | - |
dc.contributor.author | Park, Ka Hee | - |
dc.date.accessioned | 2021-08-11T17:24:19Z | - |
dc.date.available | 2021-08-11T17:24:19Z | - |
dc.date.issued | 2016-09 | - |
dc.identifier.issn | 0378-6471 | - |
dc.identifier.issn | 2092-9374 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/8826 | - |
dc.description.abstract | Purpose: To investigate the relationships between estimated cerebrospinal fluid pressure (CSFP) and trans-lamina cribrosa pressure difference (TLCPD) in open-angle glaucoma (OAG) in Korean population. Methods: A total of 10,801 eyes were included from the Korean National Health and Nutrition Examination Survey V. All participants (aged 19 years or older) were classified as non-glaucomatous group, OAG suspect group and OAG group. CSFP was calculated as CSFP (mm Hg) = 0.44 body mass index (kg/m(2)) + 0.16 diastolic blood pressure (mm Hg) - 0.18 age (years) - 1.91. TLCPD was calculated by subtracting CSFP from intraocular pressure. Results: The mean estimated CSFP was (8.7 +/- 3.3 mm Hg vs. 11.6 +/- 3.7 mm Hg, 11.2 +/- 3.8 mm Hg vs. 11.6 +/- 3.7 mm Hg) was lower, and the mean TLCPD (5.7 +/- 4.4 mm Hg vs. 2.2 +/- 4.4 mm Hg, 3 +/- 4.7 mm Hg vs. 2.2 +/- 4.4 mm Hg) was higher in the OAG group and in the OAG suspect group than in the non-glaucomatous control group, respectively (p < 0.001). After adjusting relating factor with CSFP and TLCPD using simple linear regression and multivariate analyses, the mean estimated CSFP was distributed lower (p < 0.001; beta: -0.12; B: -2.306; 95% confidence interval [CI]: -2.717, -1.895) in OAG group than in non-glaucomatous group and the mean TLCPD was distributed higher (p < 0.001; beta: 0.099; B: 1.349; 95% CI: 0.977, 1.72; p < 0.001; beta: 0.118; B: 2.776; 95% CI: 2.264, 3.289) in OAG suspect group and in OAG group than in non-glaucomatous group, respectively. Conclusions: Estimated CSFP and calculated TLCPD showed essential association with OAG presence. It supports the potential role of low CSFP in the pathogenesis of OAG. | - |
dc.format.extent | 8 | - |
dc.language | 한국어 | - |
dc.language.iso | KOR | - |
dc.publisher | 대한안과학회 | - |
dc.title | Cerebrospinal Fluid Pressure and Trans-lamina Cribrosa Pressure Difference in Open-angle Glaucoma: KNHANES V | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.3341/jkos.2016.57.9.1392 | - |
dc.identifier.wosid | 000471587300008 | - |
dc.identifier.bibliographicCitation | 대한안과학회지, v.57, no.9, pp 1392 - 1399 | - |
dc.citation.title | 대한안과학회지 | - |
dc.citation.volume | 57 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 1392 | - |
dc.citation.endPage | 1399 | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002143150 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Ophthalmology | - |
dc.relation.journalWebOfScienceCategory | Ophthalmology | - |
dc.subject.keywordAuthor | Cerebrospinal fluid pressure | - |
dc.subject.keywordAuthor | Open-angle glaucoma | - |
dc.subject.keywordAuthor | Trans-lamina cribrosa pressure difference | - |
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