Distinct intrathecal interleukin-17/interleukin-6 activation in anti-N-methyl-D-aspartate receptor encephalitis
DC Field | Value | Language |
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dc.contributor.author | Byun, Jung-Ick | - |
dc.contributor.author | Lee, Soon-Tae | - |
dc.contributor.author | Moon, Jangsup | - |
dc.contributor.author | Jung, Keun-Hwa | - |
dc.contributor.author | Sunwoo, Jun-Sang | - |
dc.contributor.author | Lim, Jung-Ah | - |
dc.contributor.author | Kim, Tae-Joon | - |
dc.contributor.author | Shin, Yong-Won | - |
dc.contributor.author | Lee, Keon-Joo | - |
dc.contributor.author | Jun, Jin-Sun | - |
dc.contributor.author | Lee, Han Sang | - |
dc.contributor.author | Lee, Woo-Jin | - |
dc.contributor.author | Kim, Young-Sook | - |
dc.contributor.author | Kim, Soyun | - |
dc.contributor.author | Jeon, Daejong | - |
dc.contributor.author | Park, Kyung-Il | - |
dc.contributor.author | Jung, Ki-Young | - |
dc.contributor.author | Kim, Manho | - |
dc.contributor.author | Chu, Kon | - |
dc.contributor.author | Lee, Sang Kun | - |
dc.date.accessioned | 2021-08-11T17:24:33Z | - |
dc.date.available | 2021-08-11T17:24:33Z | - |
dc.date.issued | 2016-08-15 | - |
dc.identifier.issn | 0165-5728 | - |
dc.identifier.issn | 1872-8421 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/8846 | - |
dc.description.abstract | The aim of this study was to compare serum and cerebrospinal fluid (CSF) cytokine/chemokine levels between anti-NMDAR and anti-LGI1 encephalitis patients. Samples from fourteen anti-NMDAR encephalitis patients, ten anti-LGI1 encephalitis patients, and ten controls were analyzed for the following cytokines/chemokines: IL-1b, IL-2, IL-4, IL-5, IL-6,IL-10, IL-12, IL-13, IL-17A, IL-23, GM-CSF, IFN-gamma, TNF-alpha, and CXCL13. Compared with controls, CSF IL-17A, IL-6 and CXCL13 were elevated in anti-NMDAR encephalitis patients (post-hoc p-values 0.002, 0.011, and 0.011, respectively) but not in anti-LGI1 encephalitis patients. In the serum, only IL-2 was increased in anti-NMDAR encephalitis. Intrathecal IL-17/IL-6 activation is a characteristic of anti-NMDAR encephalitis. (C) 2016 Elsevier B.V. All rights reserved. | - |
dc.format.extent | 7 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Elsevier BV | - |
dc.title | Distinct intrathecal interleukin-17/interleukin-6 activation in anti-N-methyl-D-aspartate receptor encephalitis | - |
dc.type | Article | - |
dc.publisher.location | 네델란드 | - |
dc.identifier.doi | 10.1016/j.jneuroim.2016.05.023 | - |
dc.identifier.scopusid | 2-s2.0-84975453843 | - |
dc.identifier.wosid | 000380973000018 | - |
dc.identifier.bibliographicCitation | Journal of Neuroimmunology, v.297, pp 141 - 147 | - |
dc.citation.title | Journal of Neuroimmunology | - |
dc.citation.volume | 297 | - |
dc.citation.startPage | 141 | - |
dc.citation.endPage | 147 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Immunology | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalWebOfScienceCategory | Immunology | - |
dc.relation.journalWebOfScienceCategory | Neurosciences | - |
dc.subject.keywordPlus | T-CELLS | - |
dc.subject.keywordPlus | INTERLEUKIN-2 | - |
dc.subject.keywordPlus | MECHANISMS | - |
dc.subject.keywordPlus | PROFILES | - |
dc.subject.keywordPlus | CYTOKINE | - |
dc.subject.keywordPlus | BLOCKADE | - |
dc.subject.keywordPlus | SPECTRUM | - |
dc.subject.keywordPlus | PATIENT | - |
dc.subject.keywordAuthor | Cytokine | - |
dc.subject.keywordAuthor | Autoimmune encephalitis | - |
dc.subject.keywordAuthor | NMDAR | - |
dc.subject.keywordAuthor | LGI1 | - |
dc.subject.keywordAuthor | IL-17A | - |
dc.subject.keywordAuthor | IL-6 | - |
dc.subject.keywordAuthor | CXCL13 | - |
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