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Factors Factors Contributing to the Preference of Korean Patients with Crohn's Disease When Selecting an Anti-Tumor Necrosis Factor Agent (CHOICE Study)

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dc.contributor.authorKim, Eun Soo-
dc.contributor.authorKim, Kyeong Ok-
dc.contributor.authorJang, Byung Ik-
dc.contributor.authorLee, Chang Kyun-
dc.contributor.authorKim, Hyo Jong-
dc.contributor.authorLee, Kang-Moon-
dc.contributor.authorKim, You Sun-
dc.contributor.authorEun, Chang Soo-
dc.contributor.authorJung, Sung-Ae-
dc.contributor.authorYang, Suk-Kyun-
dc.contributor.authorLee, Jun-
dc.contributor.authorKim, Tae-Oh-
dc.contributor.authorJung, Yunho-
dc.contributor.authorSeo, Geom Seog-
dc.contributor.authorYoon, Soon Man-
dc.date.accessioned2021-08-11T17:44:40Z-
dc.date.available2021-08-11T17:44:40Z-
dc.date.issued2016-05-
dc.identifier.issn1976-2283-
dc.identifier.issn2005-1212-
dc.identifier.urihttps://scholarworks.bwise.kr/sch/handle/2021.sw.sch/9165-
dc.description.abstractBackground/Aims: Two comparable anti-tumor necrosis factor (TNF) agents with different routes of administration (intravenous [iv] infliximab [IFX] vs subcutaneous [sc] adalimumab [ADA]) are available for patients with Crohn's disease (CD) in Korea. This study aimed to identify the preferences of Korean CD patients for a specific anti-TNF agent and the factors contributing to the decision. Methods: A prospective survey was performed among anti-TNF-naive CD patients in 10 tertiary referral hospitals. A 16-item questionnaire addressed patient preferences and the factors contributing to the decision in favor of a particular anti-TNF agent. A logistic regression was conducted to assess predictive factors for ADA preference. Results: Overall, 189 patients (139 males; mean age, 32.47 +/- 11.71 years) completed the questionnaire. IFX and ADA were preferred by 63.5% (120/189) and 36.5% (69/189) of patients, respectively. The most influential reason for choosing IFX was 'doctor's presence' (68.3%, 82/120), and ADA was "easy to use" (34.8%, 24/69). Amid various clinicodemographic data, having a >60-minute travel time to the hospital was a significant independent predictive factor for ADA preference. Conclusions: A large number of anti-TNF-naive Korean patients with CD preferred anti-TNFs with an iv route of administration. The reassuring effect of a doctor's presence might be the main contributing factor for this decision.-
dc.format.extent8-
dc.language영어-
dc.language.isoENG-
dc.publisher거트앤리버 발행위원회-
dc.titleFactors Factors Contributing to the Preference of Korean Patients with Crohn's Disease When Selecting an Anti-Tumor Necrosis Factor Agent (CHOICE Study)-
dc.typeArticle-
dc.publisher.location대한민국-
dc.identifier.doi10.5009/gnl15126-
dc.identifier.scopusid2-s2.0-84969217881-
dc.identifier.wosid000375350000014-
dc.identifier.bibliographicCitationGut and Liver, v.10, no.3, pp 391 - 398-
dc.citation.titleGut and Liver-
dc.citation.volume10-
dc.citation.number3-
dc.citation.startPage391-
dc.citation.endPage398-
dc.type.docTypeArticle-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.description.journalRegisteredClasskci-
dc.relation.journalResearchAreaGastroenterology & Hepatology-
dc.relation.journalWebOfScienceCategoryGastroenterology & Hepatology-
dc.subject.keywordPlusINFLAMMATORY-BOWEL-DISEASE-
dc.subject.keywordPlusSHARED DECISION-MAKING-
dc.subject.keywordPlusULCERATIVE-COLITIS-
dc.subject.keywordPlusINFLIXIMAB-
dc.subject.keywordPlusADALIMUMAB-
dc.subject.keywordPlusEFFICACY-
dc.subject.keywordPlusSAFETY-
dc.subject.keywordPlusPARTICIPATION-
dc.subject.keywordPlusMAINTENANCE-
dc.subject.keywordPlusREMISSION-
dc.subject.keywordAuthorCrohn disease-
dc.subject.keywordAuthorInfliximab-
dc.subject.keywordAuthorAdalimumab-
dc.subject.keywordAuthorPreference-
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