정맥 내 지질 유탁액 치료 후 성공적으로 회복한 초오 중독 1례A Case of Aconite Poisoning Successfully Recovered after Intravenous Fat Emulsion Therapy
- Other Titles
- A Case of Aconite Poisoning Successfully Recovered after Intravenous Fat Emulsion Therapy
- Authors
- 신희준; 임훈
- Issue Date
- 2016
- Publisher
- 대한임상독성학회
- Keywords
- Aconitine; Aconitum; Antidotes; Intravenous fat emulsions
- Citation
- 대한임상독성학회지, v.14, no.1, pp 60 - 65
- Pages
- 6
- Journal Title
- 대한임상독성학회지
- Volume
- 14
- Number
- 1
- Start Page
- 60
- End Page
- 65
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/9745
- DOI
- 10.22537/jksct.2016.14.1.60
- ISSN
- 1738-1320
2508-6332
- Abstract
- Aconitum is a genus of various species of flowering plants that belongs to the Family Ranunculaceae. Most Aconitum sp. have extremely toxic alkaloid substances such as aconitine, mesaconitine and hypaconitine. Among these substances, aconitine can cause fatal cardiotoxicity by activating sodium channels followed by calcium channels in myocardial cells. Even though there have been various therapeutic plans suggested comprising antidotes based on diverse case reports and studies, there is no confirmatory treatment protocol for aconite poisoning. Here, we report an aconite poisoning patient who had refractory ventricular tachyarrhythmia that did not respond to intravenous amiodarone therapies even though they were sustained for over 2 hours, but showed successful recovery following intravenous fat emulsions (IFE) therapy.
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