Prognosis of Differentiated Thyroid Carcinoma with Initial Distant Metastasis: A Multicenter Study in Korea
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김호수[김호수] | - |
dc.contributor.author | 김혜인[김혜인] | - |
dc.contributor.author | 김선욱[김선욱] | - |
dc.contributor.author | 정재훈[정재훈] | - |
dc.contributor.author | 전민지[전민지] | - |
dc.contributor.author | 김원구[김원구] | - |
dc.contributor.author | 김태용[김태용] | - |
dc.contributor.author | 김희경[김희경] | - |
dc.contributor.author | 강호철[강호철] | - |
dc.contributor.author | 한지민[한지민] | - |
dc.contributor.author | 조윤영[조윤영] | - |
dc.contributor.author | 김태혁[김태혁] | - |
dc.contributor.author | 정재훈[정재훈] | - |
dc.date.accessioned | 2021-07-29T20:26:16Z | - |
dc.date.available | 2021-07-29T20:26:16Z | - |
dc.date.created | 2020-07-15 | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 2093-596X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/skku/handle/2021.sw.skku/22958 | - |
dc.description.abstract | Background: Most patients with differentiated thyroid cancer (DTC) have a favorable prognosis. However, patients with DTC and initial distant metastasis have not been commonly found, and their clinical characteristics have seldom been reported. In this study, we analyzed the clinical features and prognosis of patients with DTC and initial distant metastasis in Korea. Methods: We retrospectively reviewed the clinical data of 242 patients with DTC and initial distant metastasis treated from 1994 to 2013, collected from five tertiary hospitals in Korea. Results: The patients’ median age was 51 years, and 65% were women. They were followed for a median of 7 years. Lung was the most common site of distant metastasis: only lung 149 patients (62%), only bone 49 (20%), other single site one (pleura), and combined sites 43 (40 were lung and bone, two were bone and other site, and one was lung and other site). At the time of diagnosis, 50 patients (21%) had non-radioactive iodine (RAI) avidity. Five-year disease-specific survival (DSS) was 85% and 10-year DSS was 68%, which were better than those in previous studies. After multivariate analysis, old age, male sex, metastatic site, and histologic type (follicular type) were significant factors for poor prognosis. However, negative RAI avidity status was not a significant prognostic factor after adjusting for other variables. Conclusion:The prognosis of Korean patients with DTC and initial distant metastasis was better than in previous studies. Old age, male sex, metastasis site, and histologic type were significant prognostic factors. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | 대한내분비학회 | - |
dc.title | Prognosis of Differentiated Thyroid Carcinoma with Initial Distant Metastasis: A Multicenter Study in Korea | - |
dc.title.alternative | Prognosis of Differentiated Thyroid Carcinoma with Initial Distant Metastasis: A Multicenter Study in Korea | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | 김호수[김호수] | - |
dc.contributor.affiliatedAuthor | 김혜인[김혜인] | - |
dc.contributor.affiliatedAuthor | 김선욱[김선욱] | - |
dc.contributor.affiliatedAuthor | 한지민[한지민] | - |
dc.contributor.affiliatedAuthor | 김태혁[김태혁] | - |
dc.contributor.affiliatedAuthor | 정재훈[정재훈] | - |
dc.identifier.bibliographicCitation | Endocrinology and Metabolism, v.33, no.2, pp.287 - 295 | - |
dc.relation.isPartOf | Endocrinology and Metabolism | - |
dc.citation.title | Endocrinology and Metabolism | - |
dc.citation.volume | 33 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 287 | - |
dc.citation.endPage | 295 | - |
dc.type.rims | ART | - |
dc.identifier.kciid | ART002354989 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.subject.keywordAuthor | Differentiated thyroid cancer | - |
dc.subject.keywordAuthor | Neoplasm metastasis | - |
dc.subject.keywordAuthor | Radioactive iodine | - |
dc.subject.keywordAuthor | Prognosis | - |
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