Preoperative cardiac troponin below the 99th-percentile upper reference limit and 30-day mortality after noncardiac surgery
DC Field | Value | Language |
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dc.contributor.author | Park, J[Park, Jungchan] | - |
dc.contributor.author | Hyeon, CW[Hyeon, Cheol Won] | - |
dc.contributor.author | Lee, SH[Lee, Seung-Hwa] | - |
dc.contributor.author | Lee, SM[Lee, Sangmin Maria] | - |
dc.contributor.author | Yeo, J[Yeo, Junghyun] | - |
dc.contributor.author | Yang, K[Yang, Kwangmo] | - |
dc.contributor.author | Min, JJ[Min, Jeong Jin] | - |
dc.contributor.author | Lee, JH[Lee, Jong Hwan] | - |
dc.contributor.author | Yang, JH[Yang, Jeong Hoon] | - |
dc.contributor.author | Song, YB[Song, Young Bin] | - |
dc.contributor.author | Hahn, JY[Hahn, Joo-Yong] | - |
dc.contributor.author | Choi, SH[Choi, Seung-Hyuk] | - |
dc.contributor.author | Choi, JH[Choi, Jin-Ho] | - |
dc.contributor.author | Gwon, HC[Gwon, Hyeon-Cheol] | - |
dc.date.accessioned | 2021-07-28T06:50:47Z | - |
dc.date.available | 2021-07-28T06:50:47Z | - |
dc.date.created | 2021-02-05 | - |
dc.date.issued | 2020-10-12 | - |
dc.identifier.issn | 2045-2322 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/skku/handle/2021.sw.skku/2852 | - |
dc.description.abstract | Preoperative high-sensitivity cardiac troponin (hs-cTn) above the 99th-percentile upper reference limit ( URL) is associated with mortality after noncardiac surgery. This study aimed to evaluate whether preoperative hs- cTn concentrations above the lowest limit of detection (LOD) but below the 99th-percentile URL can predict mortality after noncardiac surgery.From January 2010 to April 2019, a total of 12,415 noncardiac surgical patients with preoperative hs-cTn I below the 99th-percentile URL were enrolled. The patients were divided into two groups according to preoperative hs-cTn I concentration: (1) [hs-cTn] below the LOD (6 ng/L), and (2) mildly elevated [hs-cTn] but below the 99th-percentile URL (40 ng/L). The primary outcome was 30-day mortality. Of the 12,415 patients enrolled, 7958 ( 64.1%) were in the LOD group whereas 4457 (35.9%) were in the mild elevation group. The incidence of 30-day mortality was significantly greater in the mild elevation group (2.1% vs. 4.0% hazard ratio [HR] 1.73; 95% confidence interval [CI] 1.39-2.16; p < 0.001) in the multivariate analyses. The propensity score matched analyses also produced a similar result (2.6% vs. 4.2% HR 1.61; 95% CI 1.26-2.07; p < 0.001). The threshold at which the risk of mortality increased corresponded to a preoperative hs-cTn I >= 12 ng/L. Patients with preoperative hs-cTn I above the LOD and below the 99th-percentile URL had greater 30-day mortality after noncardiac surgery. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | NATURE RESEARCH | - |
dc.subject | MYOCARDIAL INJURY | - |
dc.subject | RISK | - |
dc.subject | INFARCTION | - |
dc.subject | IMPACT | - |
dc.subject | GUIDELINES | - |
dc.subject | ELEVATION | - |
dc.subject | TIME | - |
dc.title | Preoperative cardiac troponin below the 99th-percentile upper reference limit and 30-day mortality after noncardiac surgery | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Park, J[Park, Jungchan] | - |
dc.contributor.affiliatedAuthor | Lee, SH[Lee, Seung-Hwa] | - |
dc.contributor.affiliatedAuthor | Lee, SM[Lee, Sangmin Maria] | - |
dc.contributor.affiliatedAuthor | Min, JJ[Min, Jeong Jin] | - |
dc.contributor.affiliatedAuthor | Lee, JH[Lee, Jong Hwan] | - |
dc.contributor.affiliatedAuthor | Yang, JH[Yang, Jeong Hoon] | - |
dc.contributor.affiliatedAuthor | Song, YB[Song, Young Bin] | - |
dc.contributor.affiliatedAuthor | Hahn, JY[Hahn, Joo-Yong] | - |
dc.contributor.affiliatedAuthor | Choi, SH[Choi, Seung-Hyuk] | - |
dc.contributor.affiliatedAuthor | Choi, JH[Choi, Jin-Ho] | - |
dc.contributor.affiliatedAuthor | Gwon, HC[Gwon, Hyeon-Cheol] | - |
dc.identifier.doi | 10.1038/s41598-020-72853-3 | - |
dc.identifier.scopusid | 2-s2.0-85092415712 | - |
dc.identifier.wosid | 000582685800033 | - |
dc.identifier.bibliographicCitation | SCIENTIFIC REPORTS, v.10, no.1 | - |
dc.relation.isPartOf | SCIENTIFIC REPORTS | - |
dc.citation.title | SCIENTIFIC REPORTS | - |
dc.citation.volume | 10 | - |
dc.citation.number | 1 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.subject.keywordPlus | MYOCARDIAL INJURY | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | INFARCTION | - |
dc.subject.keywordPlus | IMPACT | - |
dc.subject.keywordPlus | GUIDELINES | - |
dc.subject.keywordPlus | ELEVATION | - |
dc.subject.keywordPlus | TIME | - |
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