Targetoid hepatic observations on gadoxetic acid-enhanced MRI using LI-RADS version 2018: emphasis on hepatocellular carcinomas assigned to the LR-M category
DC Field | Value | Language |
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dc.contributor.author | Park, HJ[Park, H. J.] | - |
dc.contributor.author | Kim, YK[Kim, Y. K.] | - |
dc.contributor.author | Cha, DI[Cha, D., I] | - |
dc.contributor.author | Ko, SE[Ko, S. E.] | - |
dc.contributor.author | Kim, S[Kim, S.] | - |
dc.contributor.author | Lee, ES[Lee, E. S.] | - |
dc.contributor.author | Ahn, S[Ahn, S.] | - |
dc.date.accessioned | 2021-07-28T09:47:44Z | - |
dc.date.available | 2021-07-28T09:47:44Z | - |
dc.date.created | 2020-10-05 | - |
dc.date.issued | 2020-06 | - |
dc.identifier.issn | 0009-9260 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/skku/handle/2021.sw.skku/4408 | - |
dc.description.abstract | AIM: To determine useful imaging features for differentiating hepatocellular carcinoma (HCC) categorised as LR-M from non-HCC malignancies in using the Liver Imaging-Reporting and Data System (LI-RADS) version 2018 on gadoxetic acid-enhanced magnetic resonance imaging (MRI). MATERIALS AND METHODS: Patients at high-risk for HCC with surgically confirmed HCCs (n=131) and non-HCC malignancies (n=90) and who had undergone gadoxetic acid-enhanced MRI were included. LI-RADS categories were assigned to identify hepatic observations defined as LR-M by two radiologists. Major and ancillary imaging features of hepatic observation with targetoid appearance including intratumoural septa were compared between HCCs and non-HCC malignancies. A classification tree analysis (CTA) was applied to differentiate high-risk HCCs from non-HCC malignancies in the LR-M category. RESULTS: A total of 36 HCCs (27.5%) and 70 non-HCC malignancies (77.8%) were assigned as LR-M. An enhancing capsule (p=0.0293), blood products in the mass (p=0.0393), non-targetoid restriction (p=0.018), and a septum (p=0.0053) were significantly predictive of HCC. On CTA, the presence of a septum was an initial predictor for a high probability of HCC followed by non-targetoid restriction. The CTA model has a sensitivity of 63.9%, specificity of 90%, and accuracy of 81.1% for differentiating HCC assigned LR-M from non-HCC malignancy. CONCLUSION: A considerable proportion of HCCs could have been categorised as LR-M as they had a targetoid appearance on gadoxetic acid-enhanced MRI. An intratumoural septum and non-targetoid restriction as well as enhancing capsule and blood products in the mass may be useful for differentiating HCC assigned to LR-M from non-HCC malignancy on gadoxetic acid-enhanced MRI. (C) 2020 Published by Elsevier Ltd on behalf of The Royal College of Radiologists. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | W B SAUNDERS CO LTD | - |
dc.subject | DIFFUSION-WEIGHTED IMAGES | - |
dc.subject | INTRAHEPATIC CHOLANGIOCARCINOMA | - |
dc.subject | HEPATOBILIARY PHASE | - |
dc.subject | LIVER | - |
dc.subject | CAPSULE | - |
dc.subject | CT | - |
dc.subject | DIFFERENTIATION | - |
dc.subject | CONTRAST | - |
dc.subject | FEATURES | - |
dc.subject | SEPTUM | - |
dc.title | Targetoid hepatic observations on gadoxetic acid-enhanced MRI using LI-RADS version 2018: emphasis on hepatocellular carcinomas assigned to the LR-M category | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, YK[Kim, Y. K.] | - |
dc.contributor.affiliatedAuthor | Kim, S[Kim, S.] | - |
dc.identifier.doi | 10.1016/j.crad.2020.01.002 | - |
dc.identifier.scopusid | 2-s2.0-85078952835 | - |
dc.identifier.wosid | 000531099300014 | - |
dc.identifier.bibliographicCitation | CLINICAL RADIOLOGY, v.75, no.6, pp.478.e13 - 478.e23 | - |
dc.relation.isPartOf | CLINICAL RADIOLOGY | - |
dc.citation.title | CLINICAL RADIOLOGY | - |
dc.citation.volume | 75 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 478.e13 | - |
dc.citation.endPage | 478.e23 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.subject.keywordPlus | DIFFUSION-WEIGHTED IMAGES | - |
dc.subject.keywordPlus | INTRAHEPATIC CHOLANGIOCARCINOMA | - |
dc.subject.keywordPlus | HEPATOBILIARY PHASE | - |
dc.subject.keywordPlus | LIVER | - |
dc.subject.keywordPlus | CAPSULE | - |
dc.subject.keywordPlus | CT | - |
dc.subject.keywordPlus | DIFFERENTIATION | - |
dc.subject.keywordPlus | CONTRAST | - |
dc.subject.keywordPlus | FEATURES | - |
dc.subject.keywordPlus | SEPTUM | - |
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