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Triterpene saponins from the aerial parts of Ilex cornuta and their cytotoxic activity
- Authors
- Lee S.Y.[Lee S.Y.]; Suh W.S.[Suh W.S.]; Kim H.K.[Kim H.K.]; Lee I.K.[Lee I.K.]; Choi S.U.[Choi S.U.]; Kim K.H.[Kim K.H.]; Lee K.R.[Lee K.R.]
- Issue Date
- 2015
- Keywords
- Triterpene Saponin; Ilex cornuta; Cytotoxicity
- Citation
- Heterocycles, v.91, no.6, pp.1187 - 1197
- Journal Title
- Heterocycles
- Volume
- 91
- Number
- 6
- Start Page
- 1187
- End Page
- 1197
- Abstract
- Four new triterpene saponins (1-4), together with 13 known triterpenoids (5-17), were isolated from the MeOH extract of Ilex cornuta Lindley (Aquifoliaceae). Their structures were elucidated on the basis of chemical and spectroscopic methods. The isolated compounds were tested for their cytotoxicities against four human tumor cell lines (A549, SK-OV-3, SK-MEL-2, and HCT15) in vitro using the sulforhodamine B (SRB) assay. © 2015 The Japan Institute of Heterocyclic Chemistry.
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Collections - Pharmacy > Department of Pharmacy > 1. Journal Articles
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