다중절편 방사선단층촬영 결과에 기반한 한국 중년 남성에서의 관상동맥 석회화와 심혈관질환 위험인자와의 연관성

Abstract

Objectives: The objective of this study was to investigate the relationship between coronary arterycalcification and risk factors of cardiovascular disease with multidetector computed tomography. Methods: Data were collected from 5,899 males between 30 and 59 years old by interview, survey,physical examination, blood test, and multidetector computed tomography in the university hospital fromJanuary 2010 to December 2011. We confirmed the coronary artery calcium scores of subjects bymultidetector computed tomography and identified risk factors of cardiovascular disorders. We investigated therelationship between coronary artery calcification and risk factors of cardiovascular disorders. Results: Mean calcium score of the coronary arteries in 5,899 participants was 8.20, and 773 participants(13.1%) exhibited coronary artery calcification. The presence of coronary artery calcification was correlated torisk factors of cardiovascular disease (age, blood pressure, triglyceride, HDL cholesterol, LDL cholesterol,glucose, Apolipoprotein A-1, Apolipoprotein B, body mass index, waist circumference) and risk assessmenttools of cardiovascular disorders. Significant predicted factors of coronary artery calcification had differentpatterns in each age group (30-39, 40-49, 50-59 years old). Conclusions: We confirmed the relationship between coronary artery calcification and either typical riskfactors of cardiovascular disease or risk assessment tools of cardiovascular disease. In addition, we alsoobserved that the pattern of these factors varied according to age. Therefore, age-related variation needs tobe considered in management strategies to prevent cardiovascular disease.