Reevaluation of the impact of methicillin-resistance on outcomes in patients with Staphylococcus aureus bacteremia and endocarditis
DC Field | Value | Language |
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dc.contributor.author | Joo, EJ[Joo, Eun-Jeong] | - |
dc.contributor.author | Park, DA[Park, Dong Ah] | - |
dc.contributor.author | Kang, CI[Kang, Cheol-In] | - |
dc.contributor.author | Chung, DR[Chung, Doo Ryeon] | - |
dc.contributor.author | Song, JH[Song, Jae-Hoon] | - |
dc.contributor.author | Lee, SM[Lee, Sang Moo] | - |
dc.contributor.author | Peck, KR[Peck, Kyong Ran] | - |
dc.date.accessioned | 2021-07-28T16:25:54Z | - |
dc.date.available | 2021-07-28T16:25:54Z | - |
dc.date.created | 2020-07-07 | - |
dc.date.issued | 2019-11 | - |
dc.identifier.issn | 1226-3303 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/skku/handle/2021.sw.skku/8292 | - |
dc.description.abstract | Background/Aims: Methicillin-resistant Staphylococcus aureus (MRSA) is highly prevalent in hospitals, and has recently emerged in the community. The impact of methicillin-resistance on mortality and medical costs for patients with S. aureus bacteremia (SAB) requires reevaluation. Methods: We searched studies with SAB or endocarditis using electronic databases including Ovid-Medline, Embase-Medline, and Cochrane Library, as well as five local databases for published studies during the period January 2000 to September 2011. Results: A total of 2,841 studies were identified, 62 of which involved 17,563 adult subjects and were selected as eligible. A significant increase in overall mortality associated with MRSA, compared to that with methicillin-susceptible S. aureus (MSSA), was evidenced by an odds ratio (OR) of 1.95 (95% confidence interval [CI], 1.73 to 2.21; p < 0.01). In 13 endocarditis studies, MRSA increased the risk of mortality, with an OR of 2.65 (95% CI, 1.46 to 4.80). When three studies, which compared mortality rates between CA-MRSA and CA-MSSA, were combined, the risk of methicillin-resistance increased 3.23-fold compared to MSSA (95% CI, 1.25 to 8.34). The length of hospital stay in the MRSA group was 10 days longer than that in the MSSA group (95% CI, 3.36 to 16.70). Of six studies that reported medical costs, two were included in the analysis, which estimated medical costs to be $9,954.58 (95% CI, 8,951.99 to 10,957.17). Conclusions: MRSA is still associated with increased mortality, longer hospital stays and medical costs, compared with MSSA in SAB in studies published since the year 2000. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | KOREAN ASSOC INTERNAL MEDICINE | - |
dc.subject | BLOOD-STREAM INFECTIONS | - |
dc.subject | SCCMEC TYPE-IV | - |
dc.subject | RISK-FACTORS | - |
dc.subject | CLINICAL IMPACT | - |
dc.subject | ANTIMICROBIAL TREATMENT | - |
dc.subject | MRSA BACTEREMIA | - |
dc.subject | MAJOR CAUSE | - |
dc.subject | MORTALITY | - |
dc.subject | EPIDEMIOLOGY | - |
dc.subject | PREDICTORS | - |
dc.title | Reevaluation of the impact of methicillin-resistance on outcomes in patients with Staphylococcus aureus bacteremia and endocarditis | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Joo, EJ[Joo, Eun-Jeong] | - |
dc.contributor.affiliatedAuthor | Kang, CI[Kang, Cheol-In] | - |
dc.contributor.affiliatedAuthor | Chung, DR[Chung, Doo Ryeon] | - |
dc.contributor.affiliatedAuthor | Song, JH[Song, Jae-Hoon] | - |
dc.contributor.affiliatedAuthor | Peck, KR[Peck, Kyong Ran] | - |
dc.identifier.doi | 10.3904/kjim.2017.098 | - |
dc.identifier.scopusid | 2-s2.0-85060141967 | - |
dc.identifier.wosid | 000493981500021 | - |
dc.identifier.bibliographicCitation | KOREAN JOURNAL OF INTERNAL MEDICINE, v.34, no.6, pp.1347 - + | - |
dc.relation.isPartOf | KOREAN JOURNAL OF INTERNAL MEDICINE | - |
dc.citation.title | KOREAN JOURNAL OF INTERNAL MEDICINE | - |
dc.citation.volume | 34 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1347 | - |
dc.citation.endPage | + | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002518899 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | BLOOD-STREAM INFECTIONS | - |
dc.subject.keywordPlus | SCCMEC TYPE-IV | - |
dc.subject.keywordPlus | RISK-FACTORS | - |
dc.subject.keywordPlus | CLINICAL IMPACT | - |
dc.subject.keywordPlus | ANTIMICROBIAL TREATMENT | - |
dc.subject.keywordPlus | MRSA BACTEREMIA | - |
dc.subject.keywordPlus | MAJOR CAUSE | - |
dc.subject.keywordPlus | MORTALITY | - |
dc.subject.keywordPlus | EPIDEMIOLOGY | - |
dc.subject.keywordPlus | PREDICTORS | - |
dc.subject.keywordAuthor | Methicillin resistance | - |
dc.subject.keywordAuthor | Staphylococcus aureus | - |
dc.subject.keywordAuthor | Bacteremia | - |
dc.subject.keywordAuthor | Endocarditis | - |
dc.subject.keywordAuthor | Mortality | - |
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