Bronchoalveolar lavage in fibrotic idiopathic interstitial pneumonias
DC Field | Value | Language |
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dc.contributor.author | Ryu, YJ[Ryu, Yon Ju] | - |
dc.contributor.author | Chung, MP[Chung, Man Pyo] | - |
dc.contributor.author | Han, J[Han, Joungho] | - |
dc.contributor.author | Kim, TS[Kim, Tae Sung] | - |
dc.contributor.author | Lee, KS[Lee, Kyung Soo] | - |
dc.contributor.author | Chun, EM[Chun, Eun-Mi] | - |
dc.contributor.author | Kyung, SY[Kyung, Sun Young] | - |
dc.contributor.author | Jeong, SH[Jeong, Sung Hwan] | - |
dc.contributor.author | Colby, TV[Colby, Thomas V.] | - |
dc.contributor.author | Kim, H[Kim, Hojoong] | - |
dc.contributor.author | Kwon, OJ[Kwon, O. Jung] | - |
dc.date.accessioned | 2021-08-08T01:46:28Z | - |
dc.date.available | 2021-08-08T01:46:28Z | - |
dc.date.created | 2016-11-25 | - |
dc.date.issued | 2007-03 | - |
dc.identifier.issn | 0954-6111 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/skku/handle/2021.sw.skku/84794 | - |
dc.description.abstract | The purpose of this study was to assess the role of bronchoalveolar lavage (BAL) in differentiating usual interstitial peumonia (UIP) from non-specific interstitial pneumonia (NSIP) and in predicting the prognosis in fibrotic idiopathic interstitial pneumonia (IIP). A retrospective review of 122 patients (age 58+8 years, 70 mate) with UIP (n = 87) and NSIP (n = 35) was carried out. Prior to surgical lung biopsy, all of them underwent BAL and high-resolution-computed tomography (HRCT) of the chest. Neutrophil count in BAL fluid was higher in UIP (7.0%) than NSIP (3.0%) (P = 0.027). In contrast, BAL lymphocyte count was significantly higher in NSIP (29.0%) than UIP (5.5%) (P < 0.0001). In 62 patients whose HRCT findings were atypical for UIP, BAL lymphocytosis was more frequently observed in NSIP (20/33) than UIP (4/29) (P < 0.001) and the absence of BAL lymphocytosis suggested a diagnosis of UIP rather than NSIP (odds ratio 12.7, P < 0.001). Pathologic diagnosis of NSIP was the only independent factor predicting a longer survival of our patients (median follow-up 21 months) (hazard ratio (HR) 0.035, P = 0.005). When NSIP was not included in the survival analysis, higher BAL lymphocyte count was the only independent predictor of a longer survival (HR 0.909, P = 0.029). BAL is an useful non-invasive tool. in fibrotic IIP, not only for excluding a variety of specific non-IIP diseases but also for narrowing the differential diagnosis and predicting the prognosis in the absence of the histopathologic diagnosis. (c) 2006 Elsevier Ltd. All rights reserved. | - |
dc.publisher | W B SAUNDERS CO LTD | - |
dc.subject | CRYPTOGENIC FIBROSING ALVEOLITIS | - |
dc.subject | PULMONARY-FIBROSIS | - |
dc.subject | PROGNOSTIC-SIGNIFICANCE | - |
dc.subject | HISTOLOGIC PATTERN | - |
dc.subject | DIAGNOSIS | - |
dc.subject | PNEUMONIA/FIBROSIS | - |
dc.subject | SURVIVAL | - |
dc.subject | THERAPY | - |
dc.subject | ENTITY | - |
dc.title | Bronchoalveolar lavage in fibrotic idiopathic interstitial pneumonias | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Chung, MP[Chung, Man Pyo] | - |
dc.contributor.affiliatedAuthor | Han, J[Han, Joungho] | - |
dc.contributor.affiliatedAuthor | Kim, TS[Kim, Tae Sung] | - |
dc.contributor.affiliatedAuthor | Lee, KS[Lee, Kyung Soo] | - |
dc.contributor.affiliatedAuthor | Kim, H[Kim, Hojoong] | - |
dc.contributor.affiliatedAuthor | Kwon, OJ[Kwon, O. Jung] | - |
dc.identifier.doi | 10.1016/j.rmed.2006.06.003 | - |
dc.identifier.scopusid | 2-s2.0-33846678712 | - |
dc.identifier.wosid | 000244829500037 | - |
dc.identifier.bibliographicCitation | RESPIRATORY MEDICINE, v.101, no.3, pp.655 - 660 | - |
dc.relation.isPartOf | RESPIRATORY MEDICINE | - |
dc.citation.title | RESPIRATORY MEDICINE | - |
dc.citation.volume | 101 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 655 | - |
dc.citation.endPage | 660 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordPlus | CRYPTOGENIC FIBROSING ALVEOLITIS | - |
dc.subject.keywordPlus | PULMONARY-FIBROSIS | - |
dc.subject.keywordPlus | PROGNOSTIC-SIGNIFICANCE | - |
dc.subject.keywordPlus | HISTOLOGIC PATTERN | - |
dc.subject.keywordPlus | DIAGNOSIS | - |
dc.subject.keywordPlus | PNEUMONIA/FIBROSIS | - |
dc.subject.keywordPlus | SURVIVAL | - |
dc.subject.keywordPlus | THERAPY | - |
dc.subject.keywordPlus | ENTITY | - |
dc.subject.keywordAuthor | idiopathic interstitial pneumonia | - |
dc.subject.keywordAuthor | usual interstitial peumonia | - |
dc.subject.keywordAuthor | non-specific interstitial pneumonia | - |
dc.subject.keywordAuthor | bronchoalveolar lavage | - |
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