PRE-Operative ECHOcardiograhy for prevention of cardiovascular events after non-cardiac surgery in intermediate- and high-risk patients: protocol for a low-interventional, mixed-cohort prospective study design (PREOP-ECHO)
DC Field | Value | Language |
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dc.contributor.author | Kim, EK[Kim, Eun Kyoung] | - |
dc.contributor.author | Choi, HM[Choi, Hong-Mi] | - |
dc.contributor.author | Choi, EY[Choi, Eui-Young] | - |
dc.contributor.author | Lee, HS[Lee, Hye Sun] | - |
dc.contributor.author | Park, G[Park, Goeun] | - |
dc.contributor.author | Han, DW[Han, Dong Woo] | - |
dc.contributor.author | Lee, SE[Lee, Sang-Eun] | - |
dc.contributor.author | Park, CS[Park, Chan Seok] | - |
dc.contributor.author | Hwang, JW[Hwang, Ji-won] | - |
dc.contributor.author | Choi, JH[Choi, Jae Hyuk] | - |
dc.contributor.author | Kim, MN[Kim, Mi-Na] | - |
dc.contributor.author | Kim, HK[Kim, Hyung-Kwan] | - |
dc.contributor.author | Kim, DH[Kim, Dae-Hee] | - |
dc.contributor.author | Shin, SH[Shin, Sung-Hee] | - |
dc.contributor.author | Sohn, IS[Sohn, Il Suk] | - |
dc.contributor.author | Shin, MS[Shin, Mi-Seung] | - |
dc.contributor.author | Na, JO[Na, Jin Oh] | - |
dc.contributor.author | Cho, I[Cho, Iksung] | - |
dc.contributor.author | Lee, SH[Lee, Sun Hwa] | - |
dc.contributor.author | Park, YH[Park, Yong Hyun] | - |
dc.contributor.author | Park, TH[Park, Tae-Ho] | - |
dc.contributor.author | Kim, KH[Kim, Kye Hun] | - |
dc.contributor.author | Cho, GY[Cho, Goo-Young] | - |
dc.contributor.author | Jung, HO[Jung, Hae Ok] | - |
dc.contributor.author | Park, DG[Park, Dae-Gyun] | - |
dc.contributor.author | Hong, JY[Hong, Ji Yeon] | - |
dc.contributor.author | Kang, DH[Kang, Duk-Hyun] | - |
dc.date.accessioned | 2022-10-11T08:41:40Z | - |
dc.date.available | 2022-10-11T08:41:40Z | - |
dc.date.created | 2022-10-11 | - |
dc.date.issued | 2022-09-14 | - |
dc.identifier.issn | 1745-6215 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/skku/handle/2021.sw.skku/99887 | - |
dc.description.abstract | Background: Cardiac evaluation using transthoracic echocardiography before noncardiac surgery is common in real-world practice. However, evidence supporting preoperative echocardiography is lacking. This study aims to evaluate the additional benefit of preoperative echocardiography in predicting postoperative cardiovascular events (CVE) in noncardiac surgery. Methods: This study is designed as a multicenter, prospective study to assess the utility of preoperative echocardiography in patients undergoing intermediate- or high-risk noncardiac surgery. This trial comprises two studies: (1) a randomized controlled trial (RCT) for patients undergoing intermediate-risk surgery with fewer than three clinical risk factors from the revised cardiac risk index (intermediate-risk group) and (2) a prospective cohort study for patients undergoing intermediate-risk surgery with three or more clinical risk factors, or who undergo high-risk surgery regardless of the number of clinical risk factors (high-risk group). We hypothesize that the use of preoperative echocardiography will reduce postoperative CVEs in patients undergoing intermediate- to high-risk surgery through discovery of and further intervention for unexpected cardiac abnormalities before elective surgery. A total of 2330 and 2184 patients will be enrolled in the two studies. The primary endpoint is a composite of all-cause death; aborted sudden cardiac arrest; type I acute myocardial infarction; clinically diagnosed unstable angina; stress-induced cardiomyopathy; lethal arrhythmia, such as sustained ventricular tachycardia or ventricular fibrillation; and/or newly diagnosed or acutely decompensated heart failure within 30 days after surgery. Discussion: This study will be the first large-scale prospective study examining the benefit of preoperative echocardiography in predicting postoperative CVE. The PREOP-ECHO trial will help doctors identify patients at risk of postoperative CVE using echocardiography and thereby reduce postoperative CVEs. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | BMC | - |
dc.subject | CARDIAC RISK | - |
dc.subject | 30-DAY MORTALITY | - |
dc.subject | AORTIC-STENOSIS | - |
dc.subject | TROPONIN LEVELS | - |
dc.subject | ASSOCIATION | - |
dc.subject | GUIDELINES | - |
dc.subject | MANAGEMENT | - |
dc.subject | SOCIETY | - |
dc.subject | RECOMMENDATIONS | - |
dc.subject | COMPLICATIONS | - |
dc.title | PRE-Operative ECHOcardiograhy for prevention of cardiovascular events after non-cardiac surgery in intermediate- and high-risk patients: protocol for a low-interventional, mixed-cohort prospective study design (PREOP-ECHO) | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, EK[Kim, Eun Kyoung] | - |
dc.identifier.doi | 10.1186/s13063-022-06701-2 | - |
dc.identifier.scopusid | 2-s2.0-85137911799 | - |
dc.identifier.wosid | 000853907300001 | - |
dc.identifier.bibliographicCitation | TRIALS, v.23, no.1 | - |
dc.relation.isPartOf | TRIALS | - |
dc.citation.title | TRIALS | - |
dc.citation.volume | 23 | - |
dc.citation.number | 1 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Research & Experimental Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, Research & Experimental | - |
dc.subject.keywordPlus | CARDIAC RISK | - |
dc.subject.keywordPlus | 30-DAY MORTALITY | - |
dc.subject.keywordPlus | AORTIC-STENOSIS | - |
dc.subject.keywordPlus | TROPONIN LEVELS | - |
dc.subject.keywordPlus | ASSOCIATION | - |
dc.subject.keywordPlus | GUIDELINES | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | SOCIETY | - |
dc.subject.keywordPlus | RECOMMENDATIONS | - |
dc.subject.keywordPlus | COMPLICATIONS | - |
dc.subject.keywordAuthor | Echocardiography | - |
dc.subject.keywordAuthor | Noncardiac surgery | - |
dc.subject.keywordAuthor | Trial design | - |
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