Utilization of the respiratory virus multiplex reverse transcription-polymerase chain reaction test for adult patients at a Korean tertiary care center
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ahn, Mi Young | - |
dc.contributor.author | Choi, Seong-Ho | - |
dc.contributor.author | Chung, Ji -Won | - |
dc.contributor.author | Kim, Hye Ryoun | - |
dc.date.available | 2019-03-08T18:01:29Z | - |
dc.date.issued | 2015-01 | - |
dc.identifier.issn | 1226-3303 | - |
dc.identifier.issn | 2005-6648 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/10027 | - |
dc.description.abstract | Background/Aims: Respiratory viruses (RVs) are considered to be important respiratory pathogens in adult patients, and the multiplex reverse transcription-polymerase chain reaction (RT-PCR) test is used frequently in adult patients with respiratory infections. However, clinical data regarding utilization of the multiplex RT-PCR test for RVs are lacking. Methods: We investigated the utilization of the multiplex RT-PCR test for RVs at Chung-Ang University Hospital in Seoul, Korea, between January 2012 and April 2013. Results: During the study period, the multiplex RT-PCR test was performed for 291 adult patients. The test frequency was 4.9% of rapid influenza antigen detection tests and 0.8% of respiratory bacterial culture studies. A turnaround time of < 48 hours was observed in 25.9% of positive tests. Most of the tests were performed for admitted patients (97.9%) with a community-acquired infection (84.2%) during the flu season (82.5%). RVs were detected in 81 of 291 cases (27.8%). The RV positivity rates for community- and hospital-acquired infections did not differ (28.6% vs. 23.9%, p = 0.52). Of 166 patients with pneumonia, 44 (26.5%) had a viral infection. Among the patients with RV-associated pneumonia, an RV other than influenza was detected in 20 patients (45.4%). Conclusions: The multiplex RT-PCR test for RVs was infrequently performed at a tertiary care center, and the test results were often reported late. The test was most often performed for admitted adult patients with community-acquired infections during the flu season. The utilization of multiplex RT-PCR testing for RVs in current clinical practice should be improved. | - |
dc.format.extent | 8 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | KOREAN ASSOC INTERNAL MEDICINE | - |
dc.title | Utilization of the respiratory virus multiplex reverse transcription-polymerase chain reaction test for adult patients at a Korean tertiary care center | - |
dc.type | Article | - |
dc.identifier.doi | 10.3904/kjim.2015.30.1.96 | - |
dc.identifier.bibliographicCitation | KOREAN JOURNAL OF INTERNAL MEDICINE, v.30, no.1, pp 96 - 103 | - |
dc.identifier.kciid | ART001956117 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000347746800015 | - |
dc.identifier.scopusid | 2-s2.0-84921484526 | - |
dc.citation.endPage | 103 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 96 | - |
dc.citation.title | KOREAN JOURNAL OF INTERNAL MEDICINE | - |
dc.citation.volume | 30 | - |
dc.type.docType | Article | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | Viruses | - |
dc.subject.keywordAuthor | Respiratory tract infections | - |
dc.subject.keywordAuthor | Multiplex polymerase chain reaction | - |
dc.subject.keywordPlus | COMMUNITY-ACQUIRED PNEUMONIA | - |
dc.subject.keywordPlus | BRONCHOALVEOLAR LAVAGE | - |
dc.subject.keywordPlus | INFECTIONS | - |
dc.subject.keywordPlus | GUIDELINES | - |
dc.subject.keywordPlus | RECIPIENTS | - |
dc.subject.keywordPlus | INFLUENZA | - |
dc.subject.keywordPlus | DISEASE | - |
dc.subject.keywordPlus | ASSAYS | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
84, Heukseok-ro, Dongjak-gu, Seoul, Republic of Korea (06974)02-820-6194
COPYRIGHT 2019 Chung-Ang University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.