Association between TAP1 gene polymorphisms and alopecia areata in a Korean population
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, H. K. | - |
dc.contributor.author | Lee, H. | - |
dc.contributor.author | Lew, B. L. | - |
dc.contributor.author | Sim, W. Y. | - |
dc.contributor.author | Kim, Y. O. | - |
dc.contributor.author | Lee, S. W. | - |
dc.contributor.author | Lee, S. | - |
dc.contributor.author | Cho, I. K. | - |
dc.contributor.author | Kwon, J. T. | - |
dc.contributor.author | Kim, H. J. | - |
dc.date.available | 2019-03-08T20:39:56Z | - |
dc.date.issued | 2015-12-28 | - |
dc.identifier.issn | 1676-5680 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/11462 | - |
dc.description.abstract | The transporter 1 ATP-binding cassette sub-family B (MDR/TAP) gene (TAP1) is located in the major histocompatibility complex class II region, and forms a heterodimer that plays a key role in endogenous antigen presentation pathways. Investigation of polymorphisms identified in these loci has revealed an association with several autoimmune disorders. Alopecia areata (AA) is a common autoimmune disease resulting from T cell-induced damage to hair follicles. The present study documents for the first time a comparison between the allelic and genotypic frequencies of TAP1 single nucleotide polymorphisms (SNPs) in patients with AA and those of a control group, using a direct sequencing method. Our results suggest an association between a promoter SNP (rs2071480) and susceptibility to this disease. | - |
dc.format.extent | 8 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | FUNPEC-EDITORA | - |
dc.title | Association between TAP1 gene polymorphisms and alopecia areata in a Korean population | - |
dc.type | Article | - |
dc.identifier.doi | 10.4238/2015.December.28.31 | - |
dc.identifier.bibliographicCitation | GENETICS AND MOLECULAR RESEARCH, v.14, no.4, pp 18820 - 18827 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000371587400160 | - |
dc.identifier.scopusid | 2-s2.0-84952791682 | - |
dc.citation.endPage | 18827 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 18820 | - |
dc.citation.title | GENETICS AND MOLECULAR RESEARCH | - |
dc.citation.volume | 14 | - |
dc.type.docType | Article | - |
dc.publisher.location | 브라질 | - |
dc.subject.keywordAuthor | Alopecia areata | - |
dc.subject.keywordAuthor | Association | - |
dc.subject.keywordAuthor | Single nucleotide polymorphism | - |
dc.subject.keywordAuthor | Transporter 1 ATP-binding cassette sub-family B | - |
dc.subject.keywordPlus | GENOME-WIDE ASSOCIATION | - |
dc.subject.keywordPlus | ANTIGEN-PROCESSING TAP | - |
dc.subject.keywordPlus | CLASS-II REGION | - |
dc.subject.keywordPlus | RHEUMATOID-ARTHRITIS | - |
dc.subject.keywordPlus | MHC | - |
dc.subject.keywordPlus | SUSCEPTIBILITY | - |
dc.subject.keywordPlus | HLA | - |
dc.subject.keywordPlus | TRANSPORTERS | - |
dc.subject.keywordPlus | PATHOGENESIS | - |
dc.subject.keywordPlus | ALLELES | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Genetics & Heredity | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Genetics & Heredity | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
84, Heukseok-ro, Dongjak-gu, Seoul, Republic of Korea (06974)02-820-6194
COPYRIGHT 2019 Chung-Ang University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.