Retroduplication and loss of parental genes is a mechanism for the generation of intronless genes in Ciona intestinalis and Ciona savignyi
DC Field | Value | Language |
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dc.contributor.author | Kim, Dong Seon | - |
dc.contributor.author | Wang, Yao | - |
dc.contributor.author | Oh, Hye Ji | - |
dc.contributor.author | Choi, Dongjin | - |
dc.contributor.author | Lee, Kangseok | - |
dc.contributor.author | Hahn, Yoonsoo | - |
dc.date.available | 2019-03-08T20:41:12Z | - |
dc.date.issued | 2014-12 | - |
dc.identifier.issn | 0949-944X | - |
dc.identifier.issn | 1432-041X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/11516 | - |
dc.description.abstract | Tunicates, the sister clade of vertebrates, have miniature genomes and numerous intronless genes compared to other animals. It is still unclear how the tunicates acquired such a large number of intronless genes. Here, we analyzed sequences and intron-exon organizations of homologous genes from two closely related tunicates, Ciona intestinalis and Ciona savignyi. We found seven cases in which ancestral introns of a gene were completely lost in a species after their divergence. In four cases, both the intronless copy and the intron-containing copy were present in the genome, indicating that the intronless copy was generated by retroduplication. In the other three cases, the intron-containing copy was absent, implying it was lost after retroduplication. This result suggests that retroduplication and loss of parental genes is a major mechanism for the accumulation of intronless genes in tunicates. | - |
dc.format.extent | 6 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | SPRINGER | - |
dc.title | Retroduplication and loss of parental genes is a mechanism for the generation of intronless genes in Ciona intestinalis and Ciona savignyi | - |
dc.type | Article | - |
dc.identifier.doi | 10.1007/s00427-014-0475-y | - |
dc.identifier.bibliographicCitation | DEVELOPMENT GENES AND EVOLUTION, v.224, no.4-6, pp 255 - 260 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000344629600007 | - |
dc.identifier.scopusid | 2-s2.0-84922213077 | - |
dc.citation.endPage | 260 | - |
dc.citation.number | 4-6 | - |
dc.citation.startPage | 255 | - |
dc.citation.title | DEVELOPMENT GENES AND EVOLUTION | - |
dc.citation.volume | 224 | - |
dc.type.docType | Article | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordAuthor | Tunicate | - |
dc.subject.keywordAuthor | Loss of intron | - |
dc.subject.keywordAuthor | Retroduplication | - |
dc.subject.keywordAuthor | Ciona | - |
dc.subject.keywordPlus | CHORDATE OIKOPLEURA-DIOICA | - |
dc.subject.keywordPlus | GENOME | - |
dc.subject.keywordPlus | INSIGHTS | - |
dc.relation.journalResearchArea | Cell Biology | - |
dc.relation.journalResearchArea | Evolutionary Biology | - |
dc.relation.journalResearchArea | Developmental Biology | - |
dc.relation.journalWebOfScienceCategory | Cell Biology | - |
dc.relation.journalWebOfScienceCategory | Evolutionary Biology | - |
dc.relation.journalWebOfScienceCategory | Developmental Biology | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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